DEPARTMENT OF STEM CELL BIOLOGY

2025 

1. Verkhratsky, A., Semyanov, A. (2025). Decline and fall of aging astrocytes: the human perspective. Neural Regeneration Research, 20(6), 1713-1714.
2. Zeng, H., Zhang, Z., Zhou, D., Wang, R., Verkhratsky, A., Nie, H. (2025). Investigation of the anti-inflammatory, anti-pruritic, and analgesic effects of sophocarpine inhibiting TRP channels in a mouse model of inflammatory itch and pain. Journal of Ethnopharmacology, 337, 118882.
3. Pajarskienė, J., Vailionytė, A., Uogintė, I., Byčenkienė, S., Jonavičė, U., Uzielienė, I., Bagdonas, E., Aldonytė, R. (2025). Efects of carbon black particles on human monocyte‑derived macrophages: type‑dependent pro‑infammatory activation in vitro. Archives of Toxicology,  99(2), 787-796.
4. Yang, Y., Chen, H., Huang, S., Chen, H., Verkhratsky, A., Niu, J., Qu, Y., Yi, C. (2025). BOK-engaged mitophagy alleviates neuropathology in Alzheimer's disease. Brain, 148(2), 432-447.
5. Ciuba, K., Piotrowska, A., Chaudhury, D., Dehingia, B., Duński, E., Behr, R., Soroczyńska, K., Czystowska-Kuźmicz, M., Abbas, M., Bulanda, E., Gawlik-Zawiślak, S., Pietrzak, S., Figiel, I., Włodarczyk, J., Verkhratsky, A., Niedbała, M., Kaspera, W., Wypych, T., Wilczyński, B., Pękowska, A. (2025). Molecular signature of primate astrocytes reveals pathways and regulatory changes contributing to human brain evolution. Cell Stem Cell, 32(3), 426-444
6. Radzevičiūtė-Valčiukė, E., Mickevičiūtė, E., Želvys, A., Lekešytė, B., Malakauskaitė, P., Gečaitė, J., Malyško-Ptašinskė, V., German, N., Žalnėravičius, R., Kašėta, V., Kulbacka, J., Novickij, V. (2025). Improving bleomycin electrochemotherapy with gold nanoparticles: first in vivo study on intra-tumoral field amplification. Bioelectrochemistry, 165, 108999.
7. Popek, M., Obara-Michlewska, M., Szewczyk, Ł.M., Kołodziej, M., Perlejewski, K., Verkhratsky, A., Albrecht, J., Zielińska, M. (2025). Oedematic-atrophic astrocytes in hepatic encephalopathy. Acta Neuropathologica Communications, 13(1), 122.
8. Prokarenkaitė, R., Kuodytė, K., Gudoitytė, G., Budginaitė, E., Naumovas, D., Strainienė, E., Veličkevičius, K., Dulskas, A., Šileika, E., Venius, J., Tunaitis, V., Pivoriūnas, A., Starkuvienė, V., Stankevičius, V., Sužiedėlis, K. (2025). PARP9-PARP13-PARP14 axis tunes colorectal cancer response to radiotherapy. Journal of Experimental & Clinical Cancer Research, 44(1), 199.
9. Radzevičiūtė-Valčiukė, E., Balevičiūtė, A., Želvys, A., Suveizdė, K., Zinkevičienė, A., Kašėta, V., Malyško-Ptašinskė, V., Dobrovolskienė, N., Pašukonienė, V., Novickij, J., Girkontaitė, I., Novickij, V. (2025). .Calcium electrochemotherapy and challenges in combined treatment with dendritic cell vaccination. Pharmaceutics, 17(7), 804.
10. Pociūtė, A., Pivoriūnas, A. (2025). Glymphatic transport as a possible new mechanism for the long-range signaling of extracellular vesicles through the CNS. Bioessays, 47(9), e70040.
11. Pajarskienė, J., Vailionytė, A., Uogintė, I., Byčenkienė, S., Pociūtė, A., Bagdonas, E., Aldonytė, R. (2025). Modulative effects of carbon black and polyethylene micro-nanoplastic particles on blood-brain barrier model invitro. Food and Chemical Toxicology, 206, 115762.
12. Malakauskaitė, P., Želvys, A., Mickevičiūtė, E., Malyško-Ptašinskė, V., Lekešytė, B., Radzevičiūtė-Valčiukė, E., Kašėta, V., Novickij, V. (2025). Effects of ultra-fast nanosecond electric pulses on mitochondria transmembrane potential and oxidation. Scientific Reports, 15(1), 39778.

2024 

1. Rose, C.R., Verkhratsky, A. (2024). Sodium homeostasis and signalling: the core and the hub of astrocyte function. Cell Calcium, 117, 102817.
2. Li, B., Yu, W., Verkhratsky, A. (2024). Trace metals and astrocytes physiology and pathophysiology. Cell Calcium, 118, 102843.
3. Romenskaja, D., Jonavičė, U., Tunaitis, V., Pivoriūnas, A. (2024). Extracellular vesicles from oral mucosa stem cells promote lipid raft formation in human microglia through TLR4, P2X4R, and αVβ3/αVβ5 signaling pathways. Cell Biology International, 48(3), 358-368.
4. González-González, M.A., Conde, S.V., Latorre, R., Thébault, S.C., Pratelli, M., Spitzer, N.C., Verkhratsky, A., Tremblay, M.E., Akcora, C.G., Hernández-Reynoso, A.G. Ecker, M., Coates, J., Vincent, K.L., Ma, B. (2024).
5. Huang, X.M., Qi, J.H., Su, Y.X., Zhou, Y., Wang, Q., Huang, T.D., Xue, D.D., Zeng, Y.X., Verkhratsky, A., Zhou, B.J., Chen, H., Yi, C.J. (2024). Endothelial DR6 in blood-brain barrier malfunction in Alzheimer's disease.  Cell Death & Disease, 15(4), 258.
6. Jauregui, G.V., Vukić, D., Onyango, I.G., Arias, C., Novotný, J.S., Texlová, K., Wang, S., Kovačovicova, K.L., Polakova, N., Zelinkova, J., Čarna, M., Lacovich, V., Head, B.P., Havas, D., Mistrik, M., Zorec, R., Verkhratsky, A., Keegan, L., O'Connell, M.A., Rissman, R., Stokin, G.B. (2004). Amyloid precursor protein induces reactive astrogliosis. Acta Physiologica, 240(6), e14142.
7. Malakauskaitė, P., Želvys, A., Zinkevičienė, A., Mickevičiūtė, E., Radzevičiūtė-Valčiukė, E., Malyško-Ptašinskė, V., Lekešytė, B., Novickij, J., Kašėta, V., Novickij, V. (2024). Mitochondrial depolarization and ATP loss during high frequency nanosecond and microsecond electroporation. Bioelectrochemistry, 159, 108742.
8. Romenskaja, D., Jonavičė, U., Pivoriūnas, A. (2024). Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms. FEBS Journal, 291(16), 3706-3722.
9. Su, Y., Verkhratsky, A., Yi, C. (2024). Targeting connexins: possible game changer in managing neuropathic pain? Trends in Molecular Medicine, 30(7), 642-659.
10. Oliver, B.G., Huang, X., Yarak, R., Bai, X., Wang, Q., Zakarya, R., Reddy, K.D., Donovan, C., Kim, R.Y., Morkaya, J., Wang, B., Lung Chan, Y., Saad, S., Faiz, A., Reyk, D.V., Verkhratsky, A., Yi, C., Chen, H. (2024). Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner. Environment International, 191, 108971.
11. Mazzini, L., De Marchi, F., Buzanska, L., Follenzi, A., Glover, J.C., Gelati, M., Lombardi, I., Maioli, M., Mesa-Herrera, F., Mitrečić, D., Olgasi, C., Pivoriūnas, A., Sanchez-Pernaute, R., Sgromo, C., Zychowicz, M., Vescovi, A., Ferrari, D. (2024). Current status and new avenues of stem cell-based preclinical and therapeutic approaches in amyotrophic lateral sclerosis. Expert Opinion on Biological Therapy, 24(9), 933-954.
12. Li, X., Wang, S., Zhang, D., Feng, Y., Liu, Y., Yu, W., Cui, L., Harkany, T., Verkhratsky, A., Xia, M., Li, B. (2024). The periaxonal space as a conduit for cerebrospinal fluid flow to peripheral organs. Proceedings of the National Academy of Sciences of the United States of America, 121(45), e2400024121.
13. Pociūtė, A., Kriaučiūnaitė, K., Kaušylė, A., Zablockienė, B., Alčauskas, T., Jelinskaitė, A., Rudėnaitė, A., Jančorienė, L., Ročka, S., Verkhratsky, A., Pivoriūnas, A. (2024). Plasma of COVID-19 patients does not alter electrical resistance of human endothelial blood-brain barrier in vitro. Function, 5(2), zqae002.
14. Pociūtė, A., Pivoriūnas, A., Verkhratsky, A. (2024). Astrocytes dynamically regulate the blood-brain barrier in the healthy brain. Neural Regeneration Research, 19(4), 709-710.
15. Lim, D., Verkhratsky, A. (2024). Alterations of protein homeostasis in Alzheimer's disease: beyond Procrustean bed of endoplasmic reticulum stress and unfolded protein response. Neural Regeneration Research, 19(8), 1645-1646.
16. Garaschuk, O., Verkhratsky, A. (2024)  Sleep, calcium and microglia - an (un)expected liaison. Cell Calcium, 119, 102872.
17. Verkhratsky, A., Rose, C.R. (2024). Multiple ions control astroglial excitability, or "Nein, Kalzium, ist NICHT alles". Acta Physiologica, 240(4), e14120.

Monograph:

1. Awogbindin, I., Wanklin, M., Verkhratsky, A., Tremblay, M.È. (2024). Microglia in neurodegenerative diseases. Advances in Neurobiology, 37, 497-512.
2. Garaschuk, O., Verkhratsky, A. (2024). Calcium signalling in nicroglia. Advances in Neurobiology, 37, 123-133.
3. Tremblay, M.È., Verkhratsky, A. (2024). General pathophysiology of microglia. Advances in Neurobiology, 37, 3-14.

2023 

1. Toman, M., Wade, J.J., Verkhratsky, A., Dallas, M., Bithell, A., Flanagan, B., Harkin, J., McDaid, L. (2023). The influence of astrocytic leaflet motility on ionic signalling and homeostasis at active synapses. Scientific Reports, 13(1), 3050.
2. Verkhratsky, A., Pivoriūnas, A. (2023). Astroglia support, regulate and reinforce brain barriers. Neurobiology of Disease, 179, 106054.
3. Beltran-Lobo, P., Reid, M.J., Jimenez-Sanchez, M., Verkhratsky, A., Perez-Nievas, B.G., Noble, W. (2023). Astrocyte adaptation in Alzheimer's disease: a focus on astrocytic P2X7R. Essays in Biochemistry, 67(1), 119-130.
4. Kriaučiūnaitė, K., Pociūtė, A., Kaušylė, A., Verkhratsky, A., Pivoriūnas, A. (2023). Basic fibroblast growth factor opens and closes the endothelial blood–brain barrier in a concentration‑dependent manner. Neurochemical Research, 48(4), 1211-1221.
5. Ji, M., Gong, W.L., Wang, S.M., Zhang, D.J., Chen, B.J., Li, X.Y., Wu, X.F., Cui, L.L., Feng, Y.L., Verkhratsky, A.,  Li, B. (2023). Leptin attenuates fear memory by inhibiting astrocytic NLRP3 inflammasome in post-traumatic stress disorder model. Neurochemical Research, 48(4), 1180-1190.
6. Lim, D., Tapella, L., Dematteis, G., Genazzani, A.A., Corazzari, M., Verkhratsky, A. (2023). The endoplasmic reticulum stress and unfolded protein response in Alzheimer's disease: A calcium dyshomeostasis perspective. Ageing Research Reviews, 87, 101914.
7. Radzevičiūtė-Valčiukė, E., Gečaitė, J., Želvys, A., Zinkevičienė, A., Žalnėravičius, R., Malyško-Ptašinskė, V., Nemeikaitė-Čėnienė, A., Kašėta, V., German, N., Novickij, J., Ramanavičienė, A., Kulbacka, J., Novickij, V. (2023). Improving nonviral gene delivery using MHz bursts of nanosecond pulses and gold nanoparticles for electric field amplification. Pharmaceutics, 15(4), 1178.
8. Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S.A., Abrams, J.M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E.S., Altucci, L., Amelio, I., Andrews, D.W., Aqeilan, R.I.,  Arama, E., Baehrecke, E.H., Balachandran, S., Bano, D.,  Barlev, N.A., Bartek, J., Bazan, N.G., Becker, C., Bernassola, F., Bertrand, M.J.M., Bianchi, M.E., Blagosklonny, M.V., Blander, J.M., Blandino, G., Blomgren, K., Borner, C., Bortner, C.D., Bove, P., Boya, P., Brenner, C., Broz, P.,  Brunner, T., Damgaard, R.B., Calin, G.A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F.K-M., Chen, G-Q., Chen, Q., Chen, Y.H., Cheng, E.H., Chipuk, J.E., Cidlowski, J.A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J.R., Czabotar, P.E., D'Angiolella, V., Daugaard, M., Dawson, T.M.,  Dawson, V.L., De Maria, R., De Strooper, B., Debatin, K-M., Deberardinis, R.J., Degterev, A., Del Sal, G.,  Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S.J., Dynlacht, B.D., El-Deiry, W.F., Elrod, J.W., Engeland, K., Fimia, G.M., Galassi, C., Ganini, C., Garcia-Saez, A.J., Garg, A.D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D.R., Greene, L.A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J.M., Haupt, Y., He, S., Heery, D.M., Hengartner, M.O., Hetz, C., Hildeman, D.A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P.J.,  Kanneganti, T-D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G.L., Kepp, O., Kimchi, A., Kitsis, R.N., Klionsky, D.J., Kluck, R., Krysko, D.V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I.N., Lemasters, J.J., Liccardi, G.,  Linkermann, A., Lipton, S.A., Lockshin, R.A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J-C., Martin, S.J., Martinou, J-C., Mastroberardino, P.G., Medema, J.P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E.A., Moll, U.M., Muñoz-Pinedo, C., Murphy, D.J., Niklison-Chirou, M.V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, DS., Opferman, J.T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J.M., Pentimalli, F., Pereira, D.M., Pervaiz, S., Peter, M.E., Pinton, P., Porta, G., Prehn, J.H.M., Puthalakath, H.,  Rabinovich, G.A., Rajalingam, K., Ravichandran, K.S., Rehm, M., Ricci, J-C.V., Rizzuto, R., Robinson, N., Rodrigues, C.M.P., Rotblat, B., Rothlin, C.V., Rubinsztein, D.C., Rudel, T., Rufini, A., Ryan, K.M., Sarosiek, K.A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G.S., Silke, J., Simon, H-U., Sistigu, A., Stephanou, A., Stockwell, B.R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai. G., Tait, S.W.G., Tang, D., Tavernarakis, N., Troy, C.M., Turk, B., Urbano, N., Vandenabeele, P., Vander Berghe, T., Vander Heiden, M.G., Vanderluit, J.L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A.K., VousdenK.H., Vucic, D., Vuri, D., Wagner, E.F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H-T, Zakeri, Z., Zawacka-Pankau, J.E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G., Galluzzi, L. (2023). Apoptotic cell death in disease – current understanding of the NCCD 2023. Cell Death & Differentiation, 30, 1097–1154.
9. Yeh, C.Y., Wu, K.Y., Huang, G.J., Verkhratsky, A. (2023). Radial stem astrocytes (aka neural stem cells): identity, development, physio-pathology and therapeutic potential. Acta Physiologica, 238(2), e13967.
10. Yi, C., Verkhratsky, A., Niu, J. (2023). Pathological potential of oligodendrocyte precursor cells: terra incognita. Trends in Neurosciences,  46(7), 581-596.
11. Radzevičiūtė-Valčiukė, E., Želvys, A., Mickevičiūtė, E., Gečaitė, J., Zinkevičienė, A., Malyško-Ptašinskė, V., Kašėta, V., Novickij, J., Ivaškienė, T., Novickij, V. (2023). Calcium electrochemotherapy for tumor eradication and the potential of high-frequency nanosecond protocols. Pharmaceuticals, 16(8), 1083.
12. Fedotova, A., Brazhe, A., Doronin, M., Toptunov, D., Pryazhnikov, E., Khiroug, L., Verkhratsky, A., Semyanov, A. (2023). Dissociation between neuronal and astrocytic calcium activity in response to locomotion in mice. Function, 4(4), zqad019.
13. Li, X., Chen, B., Zhang, D., Wang, S., Feng, Y., Wu, X., Cui, L., Ji, M., Gong, W., Verkhratsky, A., Xia, M., Li, B. (2023). A novel murine model of mania. Molecular Psychiatry, 28(7), 3044-3054.
14. Verkhratsky, A., Butt, A., Li, B., Illes, P., Zorec, R., Semyanov, A., Tang, Y., Sofroniew, M.V. (2023). Astrocytes in human central nervous system diseases: a frontier for new therapies. Signal Transduction and Targeted Therapy, 8(1), 396.
15. Liu, Y., Huang, Z.N., Zhang, T.X., Han, B., Yang, G.L., Jia, D.M., Yang, L., Liu, Q., Lau, A.Y.L., Paul, F., Verkhratsky, A., Shi, F.D., Zhang, C. (2023). Bruton’s tyrosine kinase‑bearing B cells and microglia in neuromyelitis optica spectrum disorder. Journal of Neuroinflammation, 20, 309.

Monograph:

1. Verkhratsky, A., Butt, A.M. (2023). Neuroglia: Function and Pathology, Academic Press.
2. Verkhratsky, A., Semyanov, A. (2023). Astrocytes in ageing. Sub-cellular Biochemistry, 103, 253-277.

2022 

1. Augusto-Oliveira, M., Arrifano, G.P., Delage, C.I., Tremblay, M.-E., Crespo-Lopez, M.E., Verkhratsky, A. (2022). Plasticity of microglia. Biological Reviews, 97(1), 217-250.
2. Butt, A.M., Verkhratsky, A. (2022). Astrocytes regulate action potential propagation in myelinated axons: It is very crowded at the node of Ranvier. Cell Calcium, 101, Article Number 102518.
3. Mitrecic, D., Hribljan, V., Jagecic, D., Isakovic, J., Lamberto, F., Horanszky, A., Zana, M., Foldes, G., Zava, B., Pivoriūnas, A., Martinez, S., Mazzini, L., Radenovic, L., Milasin, J., Chachques, J.C., Buzanska, L., Song, M.S., Dinnyes, A. (2022). Regenerative neurology and regenerative cardiology: shared hurdles and achievements. International Journal of Molecular Sciences, 23(2), 855.
4. Zhang, M., Gong, W., Zhang, D., Ji, M., Chen, B., Chen, B., Li, X., Zhou, Y., Dong, C., Wen, G., Zhan, X., Wu, X., Cui, L., Feng, Y., Wang, S., Yuan, H., Xu, E., Xia, M., Verkhratsky, A., Li, B. (2022). Ageing related thyroid deficiency increases brain-targeted transport of liver-derived ApoE4-laden exosomes leading to cognitive impairment. Cell Death & Disease, 13, 406.
5. Li, B., Zhang, D., Verkhratsky, A. (2022). Astrocytes in post-traumatic stress disorder. Neuroscience Bulletin, 38(8), 953-965.
6. Zhao, Y., Verkhratsky, A., Tang, Y., Illes, P. (2022). Astrocytes and major depression: the purinergic avenue. Neuropharmacology, 220, 109252.
7. Balevičiūtė, A., Radzevičiūtė, E., Želvys, A., Malyško-Ptašinskė, V., Novickij, J., Zinkevičienė, A., Kašėta V., Novickij, V., Girkontaitė, I. (2022). High-frequency nanosecond bleomycin electrochemotherapy and its effects on changes in the immune system and survival. Cancers (Basel), 14(24), 6254.
8. Verkhratsky, A., Arranz, A.M., Ciuba, K., Pękowska, A. (2022). Evolution of neuroglia. Annals of the New York Academy of Sciences, 1518(1), 120-130.
9. Andersen, J.V., Schousboe, A., Verkhratsky, A. (2022). Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: Integration of the glutamate/GABA-glutamine cycle. Progress in Neurobiology, 217, 102331.
10. Zaleskis, G., Characiejus, D., Juršėnaitė, J., Žibutytė, L., Kriaučiūnaitė, K., Vanagaitė-Žičkienė, M., Darinskas, A., Jonušis, M., Pašukonienė, V. (2022). Thymus subset alterations accompanying concomitant tumor immunity mimics phenotypic patterns of cytotoxic drug doxorubicin. In Vivo, 36(3), 1106-1113.

2021 

1. Pivoriūnas, A., Verkhratsky, A. (2021). Astrocyte-derived extracellular vesicles mediate intercellular communications of the neurogliovascular unit. Neural Regeneration Research, 16(7), 1421-1422.
2. Verkhratsky, A., Augusto-Oliveira, M., Pivoriūnas, A., Popov, A., Brazhe, A., Semyanov, A. (2021). Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain. Pflugers Archiv-European Journal Of Physiology, 473(5), 753-774.
3. Kriaučiūnaitė, K., Kaušylė, A., Pajarskienė, J., Tunaitis, V., Lim, D., Verkhratsky, A., Pivoriunas, A. (2021). Immortalised hippocampal astrocytes from 3xTG-AD mice fail to support BBB integrity in vitro: role of extracellular vesicles in glial-endothelial communication. Cellular And Molecular Neurobiology, 41(3), 551-562.
4. Narbute, K., Pilipenko, V.,  Pupure, J., Klinovičs, T., Auders, J., Jonavičė, U., Kriaučiūnaitė, K., Pivoriūnas, A., Kluša, V. (2021). Time-dependent memory and gait improvement by intranasally-administered extracellular vesicles in Parkinson's disease model rats.  Cellular and Molecular Neurobiology, 41(3), 605-613.
5. Lim, D., Dematteis, G., Tapella, L., Genazzani, A.A., Calì, T., Brini, M., Verkhratsky, A. (2021). Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration. Cell Calcium, 98, 102453.
6. Augusto-Oliveira, M., Verkhratsky, A. (2021). Lifestyle‑dependent microglial plasticity: training the brain guardians. Biology Direct, 16(1), 12.
7. Pivoriūnas, A., Verkhratsky, A. (2021). Astrocyte-Endotheliocyte Axis in the Regulation of the Blood-Brain Barrier. Neurochemical Research, 46(10), 2538-2550.
8. Kriaučiūnaitė K, Pociūtė A, Kaušylė A, Pajarskienė J, Verkhratsky A, Pivoriūnas A. (2021). Concentration-dependent duality of bFGF in regulation of barrier properties of human brain endothelial cells. Journal of Cellular Physiology, 236(11), 7642-7654.
9. Jonavičė, U., Romenskaja, D., Kriaučiūnaitė, K., Jarmalavičiūtė, A., Pajarskienė, J., Kašėta, V., Tunaitis, V., Malm T., Giniatulin, R., Pivoriūnas, A. (2021). Extracellular vesicles from human teeth stem cells trigger ATP release and promote migration of human microglia through P2X4 receptor/MFG-E8-dependent mechanisms. International Journal of Molecular Sciences, 22(20), 10970.
10. Pajarskienė, J., Kašėta, V., Vaikšnoraitė, K., Tunaitis, V., Pivoriūnas, A. (2021). MicroRNA-124 acts as a positive regulator of IFN-β signaling in the lipopolysaccharide-stimulated human microglial cells. International Immunopharmacology, 101(Pt A), 108262.
11. Valenza, M., Steardo Jr. L., Steardo, L., Verkhratsky, A., Scuderi, C. (2021).  Systemic inflammation and astrocyte reactivity in the neuropsychiatric sequelae of COVID-19: focus on autism spectrum disorders. Frontiers in Cellular Neuroscience, 15, Article 748136.
12. Majewska, A.K., Verkhratsky, A., Hughes, E.G. (2021). Special issue editorial: Glial plasticity in health and disease. European  Journal of  Neuroscience, 54(5), 5643-5648.
13. Khiroug, L., Verkhratsky, A. (2021). Coming full circle: In vivo Veritas, or expanding the neuroscience frontier. Cell Calcium, 98, 102452.

1. Kalėdienė, L., Baz, M., Liubavičiūtė, A., Biziulevičienė, G., Grabauskytė, I., Bieliauskienė, R., Jovaišas, P., Jurjonas, N. (2021). Antiviral effect of honey extract Camelyn against SARSCoV-2. Journal of Advanced Biotechnology and Experimental Therapeutics, 4(3), 290-297.

2020 

1. Matijošius,  T., Pivoriūnas, A., Čebatariūnienė, A., Tunaitis, V.,  Staišiūnas, L., Stalnionis, G., Ručinskienė, A. Asadauskas, S.J. (2020). Friction reduction using Nanothin Titanium layers on anodized aluminum as potential bioceramic material. Ceramics International, 46(10), 15581-15593.
2. Kašėta, V., Kaušylė, A., Kavaliauskaitė, J., Petreikytė, M., Stirkė, A., Biziulevičienė, G. (2020). Detection of intracellular biomarkers in viable cells using millisecond pulsed electric fields. Experimental Cell Research, 389(1), 111877.
3. Andjus, P., Kosanovic, M., Milicevic, K., Gautam, M., Vainio, S.J., Jagecic, D., Kozlova, E.N., Pivoriūnas, A., Chachques, J.C., Sakaj, M., Brunello, G., Mitrecic, D., Zavan, B. (2020). Extracellular vesicles as innovative tool for diagnosis, regeneration and protection against neurological damage. International Journal of Molecular Sciences, 21(18), 6859.
4. Liubavičiūtė, A., Ivaškienė, T., Biziulevičienė, G. (2020). Modulated mesenchymal stromal cells improve skin wound healing. Biologicals, 67, 1-8.

2019 

1. Narbutė, K., Pilipenko, V., Pupure, J., Dzirkale, Z., Jonavičė, U., Tunaitis, V., Kriaučiūnaitė, K., Jarmalavičiūtė, A., Jansone, B., Klusa, V., Pivoriūnas, A. (2019). Intranasal administration of extracellular vesicles derived from human teeth stem cells improves motor symptoms and normalizes tyrosine hydroxylase expression in the substantia nigra and striatum of the 6-hydroxydopamine-treated rats. Stem Cells Translational Medicine, 8(5), 490-499.
2. Jonavičė, U., Tunaitis, V., Kriaučiūnaitė, K., Jarmalavičiūtė, A., Pivoriūnas, A. (2019). Extracellular vesicles can act as a potent immunomodulators of human microglial cells. Journal of Tissue Engineering and Regenerative Medicine, 13(2), 309-318.
3. Čebatariūnienė, A., Kriaučiūnaitė, K., Prunskaitė, J., Tunaitis, V., Pivoriūnas, A. (2019). Extracellular Vesicles Suppress Basal and Lipopolysaccharide-Induced NFκB Activity in Human Periodontal Ligament Stem Cells. Stem Cells and Development, 28(15), 1037-1049.
4. Verkhratsky, A., Rodrigues, J.J., Pivoriūnas, A., Zorec, R., Semyanov, A. (2019). Astroglial atrophy in Alzheimer’s disease. Pflügers Archiv - European Journal of Physiology, 471, 1247–1261.

TITLE: IN VITRO MODELLING OF HUMAN BLOOD BRAIN BARRIER
PATHOLOGY IN ALZHEIMER’S DISEASE
LEADER: A.Verkhratsky
FUNDING: Operational programme for the European Union funds “Development of competences of scientists, other researchers and students through practical research activities”
DURATION: 2017-2021
_____
TITLE: DEVELOPMENT OF A NEW HUMAN PLURIPOTENT STEM CELL-BASED RE-PORTER ASSAYS FOR TESTING OF ANTI-INFLAMMATORY AND ANTI-OXIDATIVE PROPERTIES OF EXOSOMES
LEADER: A. Pivoriūnas
FUNDING: Operational programme for the European Union funds
“Targeted research in smart specialisation areas”
DURATION: 2017-2021
_____
TITLE: NEW THERAPEUTIC STRATEGIES FOR CHRONIC NEURODEGENERATIVE DISEASES USING EXOSOMES DERIVED FROM HUMAN STEM CELLS
LEADER: A. Pivoriūnas
FUNDING: National research programme “Healthy ageing”
DURATION: 2015-2018

• Malakauskaite Paulina

2023-10-01 – 2027-09-30

PhD supervisor – dr. Vytautas Kašeta

Topic - Study of mitochondrial transfer and transplantation of cells of different origin and activation.

• Pociute Agne

2022-10-01 – 2026-09-30

PhD supervisor – dr. Augustas Pivoriunas

Topic - In vitro modelling of human blood brain barrier pathology in neurological disorders.

• Romenskaja - Avgul Diana

2022-10-01 – 2026-09-30

PhD supervisor – dr. Augustas Pivoriunas

Topic - The effects of extracellular vesicles on the inflammatory response of human  microglia.