(8 5) 262 8636 imc@imcentras.lt Santariškių g. 5, LT-08406, Vilnius Version for the disabled

Department of experimental, preventive and clinic medicine

PhD Diana Mieliauskaitė

Head of department, chief researcher, otorhinolaryngologist
+370 5 2618130
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PhD Diana Mieliauskaitė

Head of department, chief researcher

Education

 Vilnius University, Faculty of Medicine, MD
The topic and institution of the defended work Institute of Experimental and Clinical Medicine and Vilnius University, „Efficacy and immunoregulatory activity of recombinant interferon alfa2 in upper respiratory tract diseases”
Employment 1994-2017 State Research Institute Center for Innovative Medicine (former Institute of Experimental and Clinical Medicine), senior researcher.

2018 State Research Institute Center for Innovative Medicine, chief reasearcher.
Publications
  1. Jurgelenas D, Mieliauskaite D, Filipaviciute R. From the former Soviet Union: Socioeconomic health inequalities exist in post-communist Lithuania. BMJ. 2005; 331(7510):236
  2. Mieliauskaite D, Venalis A, Gražiene V, Kirdaite G. Bilateral parotid enlargement due to malnutrition under the influence of the media in an adolescent in Lithuania. Appetite. 2007; 49; 1: 260-62.
  3. Butkienė B, Mieliauskaite D, Serapinas P, Aninkevicius V, Juzikiene V, Stropuviene S,  Zabulyte D. Oxidant/antioxidant status and trace elements leveli in blood of patients suffering from rheumatoid arthritis. Trace Elements and Electrolytes. 2007; 24(2): 97-102.
  4. Valeikiene V, Ceremnych J, Mieliauskaite D, Alekna V. The prevalence of Parkinson’s disease among Vilnius inhabitants.  Cent. Eur. J. Med., 2008; 3 (2): 195-198.
  5. Mieliauskaite D, Venalis P, Dumalakiene I, Distler J. Relationship between serum levels of transforming growth factor β1 and clinical parameters in patients with rheumatoid arthritis and Sjögren’s syndrome secondary to rheumatoid arthritis. Autoimmunity. 2009; 42(4): 356-8.
  6. Valeikiene V, Alekna V,  Juozulynas A, Mieliauskaite D, Ceremnych J. Parkinson’s disease: the most common diagnostic mistakes in Lithuania.  Cent. Eur. J. Med. 2009, 3 (4):304-309.
  7. Mieliauskaite D, Dumalakiene I, Rugiene R, Mackiewicz Z. Expression of IL-17, IL-23 and receptors of IL-17, IL-23 in minor salivary glands of patients with primary Sjögren’s syndrome. Clinical and Developmental Immunology 2012;2012:187258.doi:10.1155/2012/187258.
  8. Stegaev V, Sillat T, Porola P, Hänninen A, Falus A, Mieliauskaite D, Buzás E, Rotar Z, Mackiewicz Z, Stark H, Chazot PL, Konttinen YT. First identification of the histamine 4 receptors (H(4) R) in healthy salivary glands and in focal sialadenitis in Sjögren’s syndrome. Arthritis Rheum. 2012;64(8):2663-8.
  9. Stegaev V, Nies AT, Porola P, Mieliauskaite D, Sánchez-Jiménez F, Urdiales JL, Sillat T, Schwelberger HG, Chazot PL, Katebe M, Mackiewicz Z, Konttinen YT, Nordström DC. Histamine transport and metabolism are deranged in salivary glands in Sjogren’s syndrome. Rheumatology (Oxford). 2013;52:1599-1608.
  10. Sudzius G, Mieliauskaite D, Butrimiene I, Siaurys A, Mackiewicz Z, Dumalakiene I. Activity of T-helper cells in patients with primary Sjogren‘s syndrome. In Vivo. 2013;27(2):263-8. 
  11. Sudzius G, Mieliauskaite D, Siaurys A, Viliene R, Butrimiene I Characiejus D., Dumalakiene I. Could the complement component C4 or its fragment C4d be a marker of the more severe conditions in patients with primary Sjögren’s syndrome? Rheumatol Int. 2014; 34(2):235-41. 
  12. Sudzius G, Mieliauskaite D, Siaurys A, Viliene R, Butrimiene I Characiejus D., Dumalakiene I. Distribution of peripheral lymphocyte populations in primary Sjogren’s syndrome patients. J Immunol Res. 2015; 2015:854706. 
  13. Gocentas A, Jascaniniene N, Pasek M, Przybylski W, Matulyte E, Mieliauskaite D, Kwilecki K, Jaszczanin J. Prevalence of generalized joint hypermobility in school-aged children from east-central Europian region Folia Morphol Warsz.). 2015; doi:10.5603/FM.a2015.0065. 
  14. Narkeviciute I, Sudzius G, Mieliauskaite D, Mackiewicz Z, Butrimiene I., Viliene R, Dumalakiene I. Are cytotoxic cells changes in peripheral blood of patients with Sjogren’s syndrome related to persistent virus infection: Suggestions and conundrums. Cell Imunol . 2016;310:120-30. 
  15. Naciute M, Mieliauskaite D, Rugiene R, Nikitenkiene R, Jancoriene L, Mauricas M, Nora-Krukle Z, Murovska M, Girkontaite I. Frequency and significance of parvovirus B19 infection in patients with rheumatoid arthritis. J Gen Virol 2016;97(12):3302-3312. doi: 10.1099/jgv.0.000621.
  16. Naciute M, Mieliauskaite D, Rugiene R, Maciunaite G, Mauricas M, Murovska M, Girkontaite I. Parvovirus B19 infection modulates the levels of cytokines in the plasma of rheumatoid arthritis patients. Cytokine. 2017;96:41-48. doi: 10.1016/j.cyto.2017.03.002
  17. Naciute M, Maciunaite G, Mieliauskaite D, Rugiene R, Zinkeviciene A, Mauricas M, Murovska M, Girkontaite I. Increased Numbers of CD4+CD25+ and CD8+CD25+ T-Cells in Peripheral Blood of Patients with Rheumatoid Arthritis with Parvovirus B19 Infection. In Vivo. 2017; 31(2):181-185.
  18. Mackiewicz Z, Mazul J, Narkeviciute I, Dumalakiene I, Butrimiene I, Viliene R, Stankeviciene I, Mieliauskaite D. Sjögren‘s syndrome: concerted triggering of sicca conditions. J Immunol Res. 2019; 2019: 2075803.  doi: 10.1155/2019/2075803
  19. Narkeviciute I, Mieliauskaite D, Mackiewicz Z., Butrimiene I., Viliene R, Dumalakiene I. Distribution of Myeloid-Derived Suppressor Cells in Rheumatoid Arthritis and Sjögren’s Syndrome. doi: 10.5606/ArchRheumatol.2019.6813.
  20. Zinkevičienė, A., Dumalakienė, I., Mieliauskaitė, D. et al. sICAM-1 as potential additional parameter in the discriminationof the Sjögren syndrome and non-autoimmune sicca syndrome: a pilot study. Clin Rheumatol. 2019; https://doi.org/10.1007/s10067-019-04621-2
Projects Principal coordinator and investigator in projects funded by Open Society of Lithuania
Principal coordinator in two projects of National Programme for people with disabilities 2003 – 2012
Investigator in FW-5 and FW-6.  (in geriatrics)
Principal investigator and investigator in research studies funded by Lithuanian Science and Studies Foundation.
Member of Steering Committee and investigator  in the project “Implementation of Higher Studies in Medical Physics and Nanophotonics” in the implementation of Measure 2.5 of the Lithuanian FW 2004-2006
Principal investigator and investigator in Researcher initiated projects funded by Research Council of Lithuania
Investigator in the Project of National Programme “Chronic non infectional diseases“ funded by Research Council of Lithuania
Investigator in the project
Investigator in the pProject of International Cooperation Programm (Lithuanian – Latvian – Chinese) funded by Reasearch Council of Lithuania
Areas of interest, directions of cooperation Sjogren‘s syndrome: etiology, pathogenesis, diagnostic markers, early diagnosis, clinical picture, prognosis

Research studies and experimental development are implemented in this department.

The aim is to examine, develop and transfer new technology in health care practice: methods of diagnostics and treatment, medical devices, advanced therapy technologies, digital solutions, the methodology of preventive health care and etc.

The main areas of  the research studies:

  • Rheumatology
  • Cardiology 
  • Phototherapy
  • Medical imaging technology
  • Digital medicine

The main fields of research

Department starts scientific research in resort science area. The greatest achievements of the department are in these fields:

Rheumatology

  • Development of the unified blood vessel examination methodology for patients with connective tissue diseases.
  • Research on joint tissue. Tasks:
    • to evaluate experimental effective  photosensitizer  or nanoparticle impact for inflammatory joint tissue;
    • to evaluate light therapeutic effect for joint tissues;
    • to select the most selective photosensitizers or synthesized nanoparticles for the destruction of inflammatory synovia.
  • The search for  diagnostic tools of aggressive synovial fibroblasts in vitro and studies of the links with the course of arthritis
  • Biomedical research of rheumatoid arthritis, psoriasis arthritis, ankylosis arthritis.
  • Research on systemic sclerosis in animal biomodels. Research on phototherapy opportunities for systemic sclerosis skin complications-scleroderma- treatment.
  • Biomedical research on Sjogren’s syndrome:
    • To analyze the frequency of primary and secondary Sjogren’s syndrome;
    • To evaluate risk factors and predictors of lymphoproliferation;
    • To develop methods for disease management.

 Cardiology

  • Development of the methods and devices for monitoring of heart activity;
  • Development of telemedicine technologies for cardiology;
  • Research of smart devices application in cardiology;
  • Research on myocardial infarction treatment using upper threshold electrostimulation.

 Phototherapy

  • Studies of light impact on connective tissue;
  • Studies of photosensitizers;
  • Development of phototherapy technologies.

 Digital medicine and bioinformatics

  • Studies of medical imaging technology;
  • Development of smart devices for motoring of human physiological functions;
  • Development  of telemedicine.

Chief Researcher
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Prof. (HP) Aleksandras Laucevičius

Chief Researcher

Education

 Medicine studies Medical Faculty at Vilnius University
The topic and institution of the defended work In 1978 defended doctoral thesis – Studies of sinoatrial atrial and antrioventricular conduction disorders in rheumatic and myocardial diseases. In 1988 defended doctor habilis dissertation at Vilnius University – Informativeness of computer analysis of diagnostic stimulation and echocardiography data in the selection of patients for cardiac surgery.
Employment Vilnius University Medical  Faculty,  Head of Clinic of the  Cardiovascular Diseases, Academician, Professor Habil. Dr,  FACC, FESC
Vilnius University Hospital Santaros klinikos Chief Specialist in Cardiovascular Medicine.
Publications
  1. Solovjova S., Ryliškytė L., Čelutkienė J., Badarienė J., Navickas R., Puronaitė R., Bieliauskaitė G., Skiauterytė E., Lisaitė G., Laucevičius A. Aortic stiffness is an independent determinant of left ventricular diastolic dysfunction in metabolic syndrome patients. Blood Pressure 2016;25(1):11-20. IF 1.808
  2. Berūkštis A., Vajauskas D., Gargalskaitė U., Misonis N., Burneikaitė G., Zakarkaitė D., Miglinas M., Laucevičius A. Impact of renal sympathetic denervation on cardiac sympathetic nerve activity evaluated by cardiac MIBG imaging. EuroIntervention 2016;11:1070-1076. IF 3.769
  3. Dadonienė J., Čypienė A., Rinkūnienė E., Badarienė J., Burca J., Sakaitė I., Kalinauskaitė G., Kumpauskaitė V., Laucevičius A. Vitamin D and functional arterial parameters in postmenopausal women with metabolic syndrome. Advances in medical sciences 2016;61:224-230. IF 1.105
  4. Kotseva K, Wood D, Bacquer DD, Backer GD, Rydén L, Jennings C,..Laucevičius A., et al. EUROASPIRE IV Investigators: Laucevičius A. (Scientific Steering Committee), Alitoit I., Badarienė J., Grabliauskaitė I., Juršytė I., Palevičiūtė E., Petrulionienė Ž., Šerpytis P., Šerpytis R., Solovjova S., Smagriūnaitė V. EUROASPIRE IV: A European Society of Cardiology survey on the lifestyle, risk factor and therapeutic management of coronary patients from 24 European countries. European Journal of Preventive Cardiology 2016;23(6):638-648. (PubMed) IF 3.319
  5. Palionis D., Berūkštis A., Misonis N., Ryliškytė L., Čelutkienė J., Zakarkaitė D., Čerlinskaitė K., Valevičiene N., Tamošiūnas A., Laucevičius A. Could careful patient selection for renal denervation warrant a positive effect on arterial stiffness and left ventricular mass reduction? Acta Cardiologica 2016;71(2):173-183. IF 0.653
  6. Čelutkienė J., Burneikaitė G., Petkevičius L., Balkevičienė L., Laucevičius A. Combination of single quantitative parameters into multiparametric model for ischemia detection is not superior to visual assessment during dobutamine stress echocardiography. Cardiovascular Ultrasound 2016;14(1):13. IF 1.337
  7. Navickas R., Gal D., Laucevičius A., Taparauskaitė A., Zdanytė M., Holvoet P. Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review. Cardiovascular Research 2016;111:322–337. IF 5.465
  8. Kotseva K., De Bacquer D., De Backer G., Rydén L., Jennings C., Gyberg V., Abreu A., Aguiar C., Conde A.C., Davletov K., Dilic M., Dolzhenko M., Gaita D., Georgiev B., Gotcheva N., Lalic N., Laucevičius A., Lovic D., Mancas S., Miličić D., Oganov R., Pajak A., Pogosova N., Reiner Ž., Vulic D., Wood D., On Behalf Of The Euroaspire Investigators. Lifestyle and risk factor management in people at high risk of cardiovascular disease. A report from the European Society of Cardiology European Action on Secondary and Primary Prevention by Intervention to Reduce Events (EUROASPIRE) IV cross-sectional survey in 14 European regions. European Journal of Preventive Cardiology 2016;23(18):2007-2018 IF 3.361
  9. Šelmytė-Besusparė A., Barysienė J., Petrikonytė D., Aidietis A., Marinskis G., Laucevičius A. Auscultatory versus oscillometric blood pressure measurement in patients with atrial fibrillation and arterial hypertension.BMC Cardiovascular Disorders 2017;17(1):87.[1-8 p.] IF 1.916
  10. Burneikaitė G., Shkolnik E., Čelutkienė J., Zuozienė G., Butkuvienė I., Petrauskienė B., Šerpytis P., Laucevičius  A., Lerman A. Cardiac shock-wave therapy in the treatment of coronary artery disease: systematic review and meta-analysis. Cardiovascular Ultrasound 2017;15:11. IF 1.463
  11. Čypienė A., Dadonienė J., Miltinienė D., Rinkūnienė E., Rugienė R., Stropuvienė S., Badarienė J., Laucevičius A. The fact not to ignore: Mean blood pressure is the main predictor of increased arterial stiffness in patients with systemic rheumatic diseases. Advances in Medical Sciences 2017;62:223–229. IF 1.211
  12. Rinkūnienė E., Butkutė E., Puronaitė R., Petrulionienė Ž., Dženkevičiūtė V., Kasiulevičius V., Laucevičius A. Arterial function parameters in patients with metabolic syndrome and severe hypertriglyceridemia. Journal of Clinical Lipidology 2017;11(4):901–907.IF 5.812
  13. Šatrauskienė A., Navickas R., Laucevičius A., Huber H.J. Identifying differential miR and gene consensus patterns in peripheral blood of patients with cardiovascular diseases from literature data. BMC Cardiovascular Disorders 2017;17:173. IF  1.832
  14. Glaveckaitė S. Palionis D., Valevičienė N., Kramena R., Laucevičius A. Acquired Gerbode defect – a rare complication of myocardial infarction (Editorial Material). Acta Cardiologica 2017;72(4):491-492. IF 0.808
  15. Slivovskaja I., Ryliškytė L, Šerpytis P., Navickas R., Badarienė J., Čelutkienė J., Puronaitė R., Ryliškienė K., Čypienė A., Rinkūnienė E., Šileikienė V., Petrauskienė B., Juocevičius A., Laucevičius A. Aerobic Training Effect on Arterial Stiffness in Metabolic Syndrome. The American Journal of Medicine 2018;131(2):148-155.
  16. Slivovskaja I., Ryliškytė L, Šerpytis P., Navickas R., Badarienė J., Čelutkienė J., Puronaitė R., Ryliškienė K., Čypienė A., Rinkūnienė E., Šileikienė V., Petrauskienė B., Juocevičius A., Laucevičius A. Aerobic Training Effect on Arterial Stiffness in Metabolic Syndrome. The American Journal of Medicine 2018;131(2):148-155. 
  17. Shkolnik E., Burneikaitė G., Čelutkienė J., Scherbak M., Zuozienė G., Petrauskienė B., Trush E., Laucevičius A., Vasyuk Y. Efficacy of cardiac shock wave therapy in patients with stable angina: The design of randomized, triple blind, sham-procedure controlled study. Anatolian Journal of Cardiology 2018;19:100-109.
  18. Kutkienė S., Petrulionienė Ž., Laucevičius A., Petrylaitė M., Maskeliūnaitė D., Puronaitė R., Kovaitė M., Kalibaitaitė I., Rinkūnienė E., Dženkevičiūtė V., Kasiulevičius V. Severe dyslipidemia and concomitant risk factors in the middle-aged Lithuanian adults: a cross-sectional cohort study. Lipids in Health and Disease 2018;17:88.[1-6]
  19. Šerpytis R., Navickaitė A., Šerpytienė E., Barysienė J., Marinskis G., Jatužis D., Petrulionienė Ž., Laucevičius A., Šerpytis P. Impact of Atrial Fibrillation on Cognitive Function, Psychological Distress, Quality of Life and Impulsiveness. The American Journal of Medicine 2018;131(6):703.e1-703.e5.
  20. Glaveckaitė S., Uždavinytė-Gatelienė E., Petrulionienė Ž., Palionis D., Valevičienė N., Kalinauskas G., Šerpytis P., Laucevičius A. Predictors of ischaemic mitral regurgitation recurrence in patients undergoing combined surgery: additional value of cardiovascular magnetic resonance imaging. Interactive Cardiovascular and Thoracic Surgery 2018;27(2):222-228. 
  21. Shkolnik E., Burneikaitė  G., Jakutis G., Scherbak M., Zuozienė G., Petrauskienė B., Trush E., Vasyuk Y., Laucevičius A., Čelutkienė J. A randomized, triple-blind trial of cardiac shock-wave therapy on exercise tolerance and symptoms in patients with stable angina pectoris. Coronary Artery Disease 2018;29(7):579-586.
  22. De Smedt D., Annemans L., De Backer G., Kotseva K., Rydčn L., Wood D., Amouyel P., Bruthans J., Cifkova R., De Sutter J., Dolzhenko M., Erglis A., Gotcheva N., Gyberg V., Laucevičius A., Lovic D., Oganov R., Pajak A., Pogosova N., Reiner Ž., Stagmo M., De Bacquer D. Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey. International Journal of Cardiology 2018;272:20-25.
  23. Dadonienė J., Čypienė A., Rinkūnienė E., Badarienė J., Laucevičius A. Vitamin D, cardiovascular and bone health in postmenopausal women with metabolic syndrome. Advances in Clinical and Experimental Medicine 2018;27(11):1555-1560.
  24. 24.  Kutkienė S., Petrulionienė Ž., Laucevičius A., Matuzevičienė G., Kasiulevičius V.,   Petrulionytė E., Staigytė J., Šaulytė A., Gargalskaitė U., Skiauterytė E., Kovaitė M., Rinkūnienė E. Cardiovascular risk profile of patients with atherogenic dyslipidemia in middle age Lithuanian population. Lipids in Health and Disease 2018;17:208, [p.1-7].
  25. Kutkienė S., Petrulionienė Ž., Laucevičius A., Čerkauskienė R., Staigytė J., Saulytė A., Petrulionytė E., Gargalskaitė U., Skiauterytė E., Matuzevičienė G., Kovaitė M., Rinkūnienė E. Lipid profile evaluation and severe hypercholesterolaemia screening in the middle-aged population according to nationwide primary prevention programme in Lithuania. Atherosclerosis 2018;277:267-272.
  26. Petrulioniene Ž., Gargalskaite U., Kutkienė S., Staigytė J., Čerkauskienė R., Laucevičius A. Establishing a national screening programme for familial hypercholesterolaemia in Lithuania. Atherosclerosis 2018;277:407-412.
  27. Kutkienė S., Petrulionienė Ž., Laucevičius A., Šerpytis P., Kasiulevičius V., Staigytė J.,  Šaulytė A., Petrulionytė E., Gargalskaitė U., Skiauterytė E., Matuzevičienė G., Kovaitė M., Rinkūnienė E. Cardiovascular risk assessment of dyslipidemic middle-aged adults without overt cardiovascular disease over the period of 2009–2016 in Lithuania. Lipids in Health and Disease 2018;17:233, [p.1-9].
  28. Galkine A., Dženkevičiūtė V., Šapoka V., Urbanavičius V., Petrulionienė Z., Brimas G., Laucevičius A. Effects of Body Weight Reduction On Arterial Stiffness And Endothelial Function After Bariatric Surgery In Morbidly Obese Patients: A 4-Year Clinical Study. Acta Endocrinologica (Buchar) 2018;14(4):491-497.
  29. De Bacquer D., De Smedt D., Kotseva K., Jennings C., Wood D., Rydén L., Gyberg V., Shahim B., Amouyel P., Bruthans J., Castro Conde A., Cífková R., Deckers J.W., De Sutter J., Dilic M., Dolzhenko M., Erglis A., Fras Z., Gaita D., Gotcheva N., Goudevenos J., Heuschmann P., Laucevičius A., Lehto S., Lovic D., Miličić D., Moore D., Nicolaides E., Oganov R, Pajak A., Pogosova N., Reiner Z., Stagmo M., Störk S., Tokgözoğlu L., Vulic D., Wagner M., De Backer G.; EUROASPIRE Investigators. Incidence of cardiovascular events in patients with stabilized coronary heart disease: the EUROASPIRE IV follow-up study. European Journal of Epidemiology 2019;34(3):247-258.
  30. Valaikienė J., Ryliškytė L., Valaika A., Puronaitė R., Dementavičienė J., Vaitkevičius A., Badarienė J, Butkuvienė I, Kalinauskas G., Laucevičius A. A High Prevalence of Intracranial Stenosis in Patients with Coronary Artery Disease and the Diagnostic Value of Transcranial Duplex Sonography. Journal of Stroke & Cerebrovascular Diseases 2019;28(4):1015-1021.
  31. Ryliškytė L., Navickas R., Šerpytis P., Puronaitė R., Zupkauskienė J., Jucevičienė A., Badarienė J., Rimkienė M.A., Ryliškienė K., Skiauterytė E., Laucevičius A. Association of aortic stiffness, carotid intima-media thickness and endothelial function with cardiovascular events in metabolic syndrome subjects. Blood Pressure 2019;28(2):131-138
  32. Kutkienė S., Petrulionienė  Ž., Laucevičius A., Čerkauskienė R., Samuilis A., Augaitienė V., Gedminaitė A., Juozalėnaitė G., Šaulytė A., Staigytė J., Petrulionytė E., Gargalskaitė U., Skiauterytė E., Matuzevičienė G., Kovaitė M., Nedzelskienė I. Achilles tendon ultrasonography – a useful screening tool for cardiovascular risk estimation in patients with severe hypercholesterolemia. Atherosclerosis Supplements 2019;36:6-11.
  33. Berūkštis A., Jarašūnas J., Daškevičiūtė A., Ryliškytė L., Baranauskas A., Steponėnienė R., Laucevičius A. How to interpret 24-h arterial stiffness markers: comparison of 24-h ambulatory Mobil-O-Graph with SphygmoCor office values. Blood Pressure Monitoring 2019;24:93–98.
  34. Berūkštis A., Navickas R., Neverauskaitė-Piliponienė G., Ryliškytė L., Misiūra J., Vajauskas D., Misonis N., Laucevičius A. Arterial destiffening starts early after renal artery denervation (Research Article). International Journal of Hypertension 2019, Article ID 3845690. Hindawi.
  35. Hochman J.S., Reynolds H.R., Bangalore S…Laucevičius A. Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial. JAMA Cardiology 2019;4(3):273-286.
  36. Čelutkienė J., Burneikaitė G., Shkolnik E., Jakutis G., Vajauskas D, Čerlinskaitė K, Zuozienė G., Petrauskienė B., Puronaitė R., Komiagienė R., Butkuvienė I., Steponėnienė R., Misiūra J., Laucevičius A. The effect of cardiac shock wave therapy on myocardial function and perfusion in the randomized, triple-blind, sham-procedure controlled study. Cardiovascular Ultrasound 2019;17(1):13.
  37. Kutkienė S., Petrulionienė Ž., Laucevičius A., Čerkauskienė R., Kasiulevičius V., Samuilis A., Augaitienė V., Gedminaitė A., Bieliauskienė G., Šaulytė-Mikulskienė A., Staigytė J., Petrulionytė E., Gargalskaitė U., Skiauterytė E., Matuzevičienė G., Kovaitė M., Nedzelskienė I. Is the coronary artery calcium score the first-line tool for investigating patients with severe hypercholesterolemia? Lipids in Health and Disease 2019;18(1):149. [p.1-9]
  38. Slušnienė A., Laucevičius A., Navickas P., Ryliškytė L., Stankus V., Stankus A., Navickas R., Laucevičienė I., Kasiulevičius V. Daily Heart Rate Variability Indices in Subjects with and Without Metabolic Syndrome Before and After the Elimination of the Influence of Day-Time Physical Activity. Medicina-Lithuania 2019;55(10):700 [p.1-14].
  39. Kutkienė S., Petrulionienė Ž., Karčiauskaitė D., Laucevičius A., Matuzevičienė G., Staigytė J., Šaulytė Mikulskienė A., Gargalskaitė U., Skiauterytė E., Kovaitė M. Lower than average HDL cholesterol efflux capacity in Lithuanian population. Lipids in Health and Disease 2019;18(1):186 [p.1-8].
  40. Caprnda M., Zulli A., Shiwani H.A., Kubatka P., Filipova S., Valentova V., Gazdikova K., Mozos I., Berūkštis A., Laucevičius A., Rihacek I., Dragasek J., Prosecky R., Egom E.E., Staffa R., Kruzliak P., Krasnik V. The therapeutic effect of B-type natriuretic peptides in acute decompensated heart failure. Clinical and Experimental Pharmacology & Physiology 2020;47(7):1120-1133.
  41. Laucevičius A, Rinkūnienė E, Petrulionienė Ž, Ryliškytė L, Jucevičienė A, Puronaitė R, Badarienė J, Navickas R, Mikolaitytė J, Gargalskaitė U, Dženkevičiūtė V, Kutkienė S, Gimžauskaitė S, Mainelis A, Šlapikas R, Gurevičius R, Jatužis D, Kasiulevičius V. Trends in cardiovascular risk factor prevalence among Lithuanian middle-aged adults between 2009 and 2018. Atherosclerosis. 2020;299:9-14.
  42. Slušnienė A., Navickas P., Stankus A., Laucevičienė I., Ryliškytė L., Laucevičius A. Defining the nocturnal period in 24-h ambulatory blood pressure monitoring: a comparison of three methods. Blood Pressure Monitoring 2021 Jan 14. doi: 10.1097/MBP.0000000000000509.
  43. Laučytė-Cibulskienė A., Ryliškytė L., Badaras I., Navickas P., Badarienė J., Laucevičius A. Arterial stiffness in regards to kidney function in middle-aged subjects with metabolic syndrome: Lithuanian high-risk cohort. Blood Pressure Monitoring 2021 Jan 21. doi:10.1097/MBP.0000000000000510. 
Projects Lithuanian Business Support Agency project “Development of a self-monitoring and remote monitoring system for hypertensive patients“ (No. J05-LVPA-K-03-0034).
Research Council of Lithuania project “Anaerobic threshold, cardiac rhythm variability, autonomic nervous system, physical capacity,
cardiology“ (No. S-MIP-19-63).
Areas of interest, directions of cooperation

Preventive cardiology, early detection and treatment of atherosclerosis, arterial markers, cardiometabolic risk, resistant arterial hypertension and metabolic syndrome, digital cardiology, remote patient monitoring, personalized cardiology, autonomic cardiovascular regulation.

Senior Researcher
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PhD Gailutė Kirdaitė

Senior Researcher

Education

 Medical Academy of Kaunas, MD, PhD
The topic and institution of the defended work “Protoporphyrin IX photodynamic therapy for synovitis”. University of Lausanne, Switzerland.
Employment Senior researcher fellow, State Reseach Institute for Innovative Medicine.
Publications 1. Marty I, Péclat V, Kirdaite G, Salvi R, So A, Busso N. Amelioration of collagen-induced arthritis by thrombin inhibition. J Clin Invest. 2001 Mar;107(5):631-40.
2. Kirdaite G, Lange N, Busso N, Van Den Bergh H, Kucera P, So A. Protoporphyrin IX photodynamic therapy for synovitis. Arthritis Rheum. 2002 May;46(5):1371-8.
3. Dadonene I, Redaĭtene E, Shaulauskene I, Kirdaĭte G, Vasiliauskene L. Antineutrophil cytoplasmic antibodies in patients with diffuse diseases of connective tissue. Ter Arkh. 2002;74(5):38-43. Russian.
4. Kirdaite G, Redaitiene E, Dadoniene J, Stropuviene S. Anticitrulline antibodies – new marker in rheumatoid arthritis diagnostics. Medicina (Kaunas). 2003;39(5):435-7.
5.  Redaĭtene E, Dadonene I, Kirdaĭte G, Martsiushkene E, Shapoka V. Hemostasis in patients with rheumatoid arthritis. Ter Arkh. 2005;77(4):74-7. Russian.
6. Bagdonas S, Kirdaite G, Streckyte G, Graziene V, Leonaviciene L, Bradunaite R, Venalis A, Rotomskis R. Spectroscopic study of ALA-induced endogenous porphyrins in arthritic knee tissues: targeting rheumatoid arthritis PDT. Photochem Photobiol Sci. 2005 Jul;4(7):497-502. Epub 2005 Jun 1
 7. Mieliauskaite D, Venalis A, Graziene V, Kirdaite G. Bilateral parotid enlargement due to malnutrition under the influence of the media in an adolescent in Lithuania. Appetite. 2007 Jul;49(1):260-2. Epub 2007 Jan 2.
8.  Dadoniene J, Pileckyte M, Baranauskaite A, Kirdaite G. Clinical characteristics and long-term outcomes of 35 patients with Wegener’s granulomatosis followed up at two rheumatology centers in Lithuania. Medicina (Kaunas). 2010;46(4):256-60.9. Leonavičienė L,
9. Kirdaitė G, Bradūnaitė R, Vaitkienė D, Vasiliauskas A, Zabulytė D, Ramanavičienė A, Ramanavičius A, Ašmenavičius T, Mackiewicz Z. Effect of gold nanoparticles in the treatment of established collagen arthritis in rats. Medicina (Kaunas). 2012;48(2):91-101. Epub 2012 Apr 5.
10. Rudys R, Bagdonas S, Kirdaitė G, Papečkienė J, Rotomskis R. Fluorescence morphology and fluorescence lifetime imaging microscopy (FLIM) of rabbit knee tissues in the experimental arthritis model. Medical Physics in the Baltic States: proceedings of the 10th International Conference on Medical Physics. Kaunas, Lithuania. Technology, 2012, p. 56-61.
11. Rudys R, Kirdaitė G, Bagdonas S, Leonavičienė L, Bradūnaitė R, Streckytė G, Rotomskis R. Spectroscopic assessment of endogenous porphyrins in a rheumatoid arthritis rabbit model after the application of ALA and ALA-Me. J Photochem Photobiol B. 2013 Feb 5;119:15-21.
12. Rudys R, Denkovskij J, Kirdaitė G, Bagdonas S. Induction of protoporphyrin IX in patient-derived synoviocytes, cartilage explants and chondrons after application of 5-aminolevulinic acid or its methyl ester. J Photochem Photobiol B. 2014 Dec;141:228-34.
13. Rudys R, Bagdonas S, Kirdaitė G, Papečkienė J, Rotomskis R. Multidimensional visualization of healthy and sensitized rabbit knee tissues by means of confocal microscopy. J Biomed Opt. 2015 May;20(5):051035.
14. Denkovskij J, Rudys R, Bernotiene E, Minderis M, Bagdonas S, Kirdaite G. Cell surface markers and exogenously induced PpIX in synovial mesenchymal stem cells. Cytometry A. 2015 Nov;87(11):1001-11. doi: 10.1002/cyto.a.22781. Epub 2015 Sep 10.
15. Karpec D, Rudys R, Leonaviciene L, Mackiewicz Z, Bradunaite R, Kirdaite G, Venalis A. The impact of high-dose narrowband ultraviolet A1 on dermal thickness, collagen and matrix-metalloproteinases in animal model of scleroderma. J Photochem Photobiol B. 2017 Aug;173:448-455. doi: 10.1016/j.jphotobiol.2017.06.021. Epub 2017 Jun 21.
16. Karpec D, Rudys R, Leonaviciene L, Mackiewicz Z, Bradunaite R, Kirdaite G, Venalis A. The safety and efficacy of light emitting diodes-based ultraviolet A1 phototherapy in bleomycin-induced scleroderma in mice. Adv Med Sci. 2018 Mar;63(1):152-159. doi: 10.1016/j.advms.2017.09.001. Epub 2017 Nov 6.
17. Kirdaite G, Leonaviciene L, Bradunaite R, Vasiliauskas A, Rudys R, Ramanaviciene A, Mackiewicz Z. Antioxidant effects of gold nanoparticles on early stage of collagen-induced arthritis in rats. Res Vet Sci. 2019 Jun;124:32-37. doi: 10.1016/j.rvsc.2019.02.002. Epub 2019 Feb 18.
18. Bernotiene E, Bagdonas E, Kirdaite G, Bernotas P, Kalvaityte U, Uzieliene I, Thudium CS, Hannula H, Lorite GS, Dvir-Ginzberg M, Guermazi A, Mobasheri A. Emerging Technologies and Platforms for the Immunodetection of Multiple Biochemical Markers in Osteoarthritis Research and Therapy. Front Med (Lausanne). 2020 Oct 21;7:572977. doi: 10.3389/fmed.2020.572977. eCollection 2020.
Projects 2004   
Photosensitised artritis therapy: search for diagnostic and therapeutic indices.
(Lithuanian State Science and Studies Foundation)
2005   
Reseach of photosensitizer selective accumulation in inflamed joints.
 (Lithuanian State Science and Studies Foundation)
2007   
Research of synovial lesions in patients with inflammatory arthritis.
(Lithuanian State Science and Studies Foundation)
2006 – 2008    
Medical physics and nanophotonics high degree studies realization.
(European Structural Funds)
2006 – 2008    
Research and studies centre of physics and nanophotonics technologies. 
(European Structural Funds)
2010 – 2011    
Model of rheumatoid arhritis photosensitized therapy in vitro.
(Reseach Council of Lithuania)
2010 -2011     
The interaction of inflammatory aggressive fibroblasts with gold nanoparticles in the model of arthritis.
(Reseach Council of Lithuania)
2019 – 2022
Attracting Foreign Researchers for Research Implementation (SMART): „Development of a nanobiosensor: a multiplex analysis of diagnostic biomarkers for personalization of osteoarthritis therapy“.
(Reseach Council of Lithuania)
Areas of interest, directions of cooperation

Arthritis, biomarkers, light technologies, new medical devices.

PhD Sigita Stropuvienė

Researcher

Junior Researcher (project)
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Petras Navickas

Junior Researcher (project)

Education

 Human medicine studies, Faculty of Medicine, Vilnius University, Vilnius, Lithuania. Magna cum laude master’s degree.
Employment Vilnius University Hospital Santaros Clinics, Vilnius University Faculty of Medicine. Cardiology residency. 
Publications Articles indexed in the Clarivate Analytics (ISI Web of Science) database:

  1. Serpytis P., Navickas P., Navickas A., Serpytis R., Navickas G., Glaveckaite S. Age- and gender-related peculiarities of patients with delirium in the cardiac intensive care unit. Kardiol Pol. 2017;75(10):1041-50. doi: 10.5603/KP.a2017.0122 (IF: 1,341)
  2. Lukaviciute L., Navickas P., Navickas A., Grigaitiene J., Ganceviciene R., Zouboulis CC. Quality of life, anxiety prevalence, depression symptomatology and suicidal ideation among acne patients in Lithuania. J Eur Acad Dermatol Venereol. 2017;31(11):1900-6. doi: 10.1111/jdv.14477 (IF: 3,528)
  3. Serpytis P., Navickas P., Lukaviciute L., Navickas A., Aranauskas R., Serpytis R., Deksnyte A., Glaveckaite S., Petrulioniene Z., Samalavicius R. Gender-based differences in anxiety and depression following acute myocardial infarction. Gender-Based Differences in Anxiety and Depression Following Acute Myocardial Infarction. Arq Bras Cardiol. 2018. doi: 10.5935/abc.20180161 (IF: 1,318)
  4. Slušnienė A., Laucevičius A., Navickas P., Ryliškytė L., Stankus V., Stankus A., Navickas R., Laucevičienė I., Kasiulevičius V. Daily heart rate variability indices in subjects with and without metabolic syndrome before and after the elimination of the influence of day‐time physical activity // Medicina. Basel : MDPI AG. ISSN 1010-660X. eISSN 1648-9144. 2019, vol. 55, no. 10, art. no. 700, p. 1-14. DOI: 10.3390/medicina55100700. [DB: DOAJ, MEDLINE, Scopus, Science Citation Index Expanded (Web of Science)] [IF: 1.205; AIF: 4.391; Q3 (2019 InCities JCR SCIE)] (IF: 1.467)
  5. Lukaviciute L., Ganceviciene R., Navickas P., Navickas A., Grigaitiene J, Zouboulis C. C. Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania. Dermatology. 2020. 1-9. (IF: 2.497)
  6. Slusniene A., Navickas P., Stankus A., Lauceviciene I., Ryliskyte L., Laucevicius A. Defining the nocturnal period in 24-h ambulatory blood pressure monitoring: a comparison of three methods // Blood pressure monitoring. Philadelphia : Lippincot Williams & Wilkins. ISSN 1359-5237. eISSN 1473-5725. 2021, p. [1-5]. DOI: 10.1097/MBP.0000000000000509. [DB: MEDLINE, Scopus, Science Citation Index Expanded (Web of Science)] (IF: 1.092)
  7. Laucyte-Cibulskiene A., Ryliskyte L., Badaras I., Navickas P., Badariene J., Laucevicius A. Arterial stiffness in regards to kidney function in middle-aged subjects with metabolic syndrome: Lithuanian high-risk cohort // Blood pressure monitoring. Philadelphia : Lippincott Williams & Wilkins. ISSN 1359-5237. eISSN 1473-5725. 2021, p. [1-10]. DOI: 10.1097/MBP.0000000000000510. [DB: Scopus, Science Citation Index Expanded (Web of Science)] (IF: 1.092)

Other peer-review scientific articles:

  1. Navickas A., Smirinenko A., Navickas P., Lukavičiūtė L., Dembinskas A., Gurevičius R., Aliukonienė R., Benošis A., Badaras R., Daškevičius K., Daškevičienė J. Medical and social aspects of suicide in lithuania in the first half of the XXth century. Health sciences in eastern Europe, 2016, v. 26, no. 1, p. 88–95. ISSN 1392–6373. DOI: 10.5200/sm-hs.2016.014
  1. Navickas A., Valančiūtė J., Navickas P., Lukavičiūtė L., Danilevičiūtė V. Pecularities of smoking in psychiatric and non-psychiatric wards in lithuania. Health sciences in eastern Europe, 2016, v. 26, no. 1, p. 110–116. ISSN 1392–6373. DOI: 10.5200/sm-hs.2016.017
  1. Gancevičienė R., Lukavičiūtė L., Navickas P., Navickas A., Grigaitienė J., Zouboulis CC. The impact of acne on emotional health. Health sciences in eastern Europe, 2018, v. 28, no. 3, p. 30–35. ISSN 1392–6373. DOI: 10.5200/sm-hs.2018.036
  2. Navickas P., Lukavičiūtė L., Šerpytis P., Benošis A., Šerpytis R., Daškevičius K., Navickas A. The link between ischemic heart disease and the prevalence of suicide in european union. Health sciences in eastern Europe, 2019, v. 29, no. 1, p. 42–49. ISSN 1392–6373. DOI: 10.5200/sm-hs.2019.008
  3. Skorniakov V., Mainelis A., Navickas P., Marinskis G., Stankus A. On the P-wave model of a single electrocardiogram lead. Seminars in Cardiovascular Medicine, 2021; 27:1–11. DOI: 10.2478/semcard-2021-0001
Projects Carried out in CIM:

  • Lithuanian Business Support Agency project “Development of a self-monitoring and remote monitoring system for hypertensive patients“ (No. J05-LVPA-K-03-0034).
  • Research Council of Lithuania project “Anaerobic threshold, cardiac rhythm variability, autonomic nervous system, physical capacity, cardiology“ (No. S-MIP-19-63).

Carried out in other institutions:

  • COST Action CA18216 „Network for Research in Vascular Ageing (VascAgeNet)“ (

Research Council of Lithuania No. P-COST-9-54).

  • Lithuanian Business Support Agency project “Development of a personalized physical activity efficiency assessment tool and development of an application methodology“. (No. J05-LVPA-K-01-0162).
  • Research Council of Lithuania project “Optimization of type 2 myocardial infarction diagnostics and development of treatment strategy“ (No. 09.3.3-LMT-K-712-01-0148).
Areas of interest, directions of cooperation

Digital cardiology, remote patient monitoring, personalized cardiology, artificial intelligence in cardiology, cardiovascular autonomic regulation, early vascular aging, arterial markers, cardiometabolic risk.

Chief Researcher
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Prof. Jelena Čelutkienė

Chief Researcher

Education

 PhD degree
The topic and institution of the defended work “Markers of myocardial ischemia in spectral Doppler analysis data”, Vilnius University
Employment CIM, Chief Researcher
Publications
  1. Zuozienė G., Leibowitz D., Čelutkienė J., Burneikaitė G., Ivaškevičienė L., Kalinauskas G., Maneikienė V.V., Palionis D., Janušauskas V., Valevičienė N. Laucevičius A. Multimodality imaging of myocardial revasculalarization using cardiac shock wave therapy. International Journalof Cardiology 2015;187:229-230. IF 6.175 Q1
  2. Bogomolovas J., Brohm K., Čelutkienė J., Balčiūnaitė G., Bironaitė D., Bukelskienė V., Daunoravičus D., Witt C.C., Fielitz J., Grabauskienė V., Labeit S. Induction of Ankrd1 in Dilated Cardiomyopathy Correlates with the Heart Failure Progression. Biomed Research International 2015 (2015), Article ID 273936, 9 pages. IF 1.579. Q3
  3. Solovjova S., Ryliškytė L., Čelutkienė J., Badarienė J., Navickas R., Puronaitė R., Bieliauskaitė G., Skiauterytė E., Lisaitė G., Laucevičius A. Aortic stiffness is an independent determinant of left ventricular diastolic dysfunction in metabolic syndrome patients. Blood Pressure 2016;25(1):11-20. IF 1.391 Q3
  4. Palionis D., Berūkštis A., Misonis N., Ryliškytė L., Čelutkienė J., Zakarkaitė D., Čerlinskaitė K., Valevičiene N., Tamošiūnas A., Laucevičius A. Could careful patient selection for renal denervation warrant a positive effect on arterial stiffness and left ventricular mass reduction? Acta Cardiologica 2016;71(2):173-183. IF 0.653 Q4
  5. Čelutkienė J., Burneikaitė G., Petkevičius L., Balkevičienė L., Laucevičius A. Combination of single quantitative parameters into multiparametric model for ischemia detection is not superior to visual assessment during dobutamine stress echocardiography. Cardiovascular Ultrasound 2016;14(1):13. IF 1.337 Q3
  6. Harjola V.P., Mebazaa A., Čelutkienė J. et al. Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology. European Journal of Heart Failure 2016;18(3):226-241. IF 6.968 Q1
  7. Kataoka A., Scherrer-Crosbie M., Senior R., Garceau P., Valbuena S., Čelutkienė J., et al. Transient Ischemic Dilatation during Stress Echocardiography: An Additional Marker of Significant Myocardial Ischemia. ECHOCARDIOGRAPHY – A Journal Of Cardiovascular Ultrasound And Allied Techniques 2016;33(8):1202-1208. IF 1.432 Q3
  8. Van Aelst L.N., Čelutkienė J., Mebazaa A. Advanced heart failure: look right to prognosticate right! European Journal of Heart Failure 2016;18(5):573-575. IF 6.968 Q1
  9. Burneikaitė G., Shkolnik E., Čelutkienė J., Zuozienė G., Butkuvienė I., Petrauskienė B., Šerpytis P., Laucevičius  A., Lerman A. Cardiac shock-wave therapy in the treatment of coronary artery disease: systematic review and meta-analysis. Cardiovascular Ultrasound 2017;15:11. IF 1.463 Q3
  10. Kluonaitis K., Glaveckaitė S., Balčiūnaitė G., Juškaitė A., Palionis D., Valevičienė N., Mickys U., Katkus R., Fontes-Carvalho R., Čelutkienė J. Cardiac sarcoidosis – diagnostic challenges due to unusual clinical presentation (Letter). Hellenic Journal of Cardiology 2017;58(4):310-313. IF 0.94 Q4
  11. Motiejūnaitė J., Čelutkienė J., Mebazaa A. The right ventricle drives the progression of heart failure [Letter]. European Journal of Heart Failure 2017;19(12):1737. IF 6.968 Q1
  12. Ciampi Q, Picano E, Paterni M, Daros CB, Simova I, de Castro E Silva Pretto JL, Scali MC, Gaibazzi N, Severino S, Djordjevic-Dikic A, Kasprzak JD, Zagatina A, Varga A, Lowenstein J, Merlo PM, Amor M, Čelutkienė J., et al. Quality control of regional wall motion analysis in stress Echo 2020. International Journal of Cardiology 2017;249:479-485. IF 6.189 Q1
  13. Gorter T.M., van Veldhuisen D.J., Bauersachs J., Borlaug B.A., Čelutkienė J., Coats A.J.S., Crespo-Leiro M.G., Guazzi M., Harjola V.P., Heymans S., Hill L., Lainscak M., Lam C.S.P., Lund L.H., Lyon A.R., Mebazaa A., Mueller C., Paulus W.J., Pieske B., Piepoli M.F., Ruschitzka F., Rutten F.H., Seferovic P.M., Solomon S.D., Shah S.J., Triposkiadis F., Wachter R., Tschöpe C., de Boer R.A. Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology (Review). European Journal of Heart Failure 2018;20(1):16-37. IF 12.129 Q1
  14. Doehner W., Ural D., Haeusler K.G., Čelutkienė J., Bestetti R., Cavusoglu Y., Peña-Duque M.A., Glavas D., Iacoviello M., Laufs U., Alvear R.M., Mbakwem A., Piepoli M.F., Rosen S.D., Tsivgoulis G., Vitale C., Yilmaz M.B., Anker S.D., Filippatos G., Seferovic P., Coats A.J.S., Ruschitzka F. Heart and brain interaction in patients with heart failure: overview and proposal for a taxonomy. A position paper from the Study Group on Heart and Brain Interaction of the Heart Failure Association. European Journal of Heart Failure 2018;20(2):199-215. IF 6.968 Q1
  15. Slivovskaja I., Ryliškytė L, Šerpytis P., Navickas R., Badarienė J., Čelutkienė J., Puronaitė R., Ryliškienė K., Čypienė A., Rinkūnienė E., Šileikienė V., Petrauskienė B., Juocevičius A., Laucevičius A. Aerobic Training Effect on Arterial Stiffness in Metabolic Syndrome. The American Journal of Medicine 2018;131(2):148-155. IF 5.55 Q1
  16. Shkolnik E., Burneikaitė G., Čelutkienė J., Scherbak M., Zuozienė G., Petrauskienė B., Trush E., Laucevičius A., Vasyuk Y. Efficacy of cardiac shock wave therapy in patients with stable angina: The design of randomized, triple blind, sham-procedure controlled study. Anatolian Journal of Cardiology 2018;19(2):100-109. IF 1.19 Q3
  17. Akiyama E., Van Aelst L.N.L, Arrigo M., Lassus J., Miró Ò., Čelutkienė J., Choi D.J., Cohen-Solal A., Ishihara S., Kajimoto K., Laribi S., Maggioni A.P., Motiejūnaitė J., Mueller C., Parenica J., Park J.J., Sato N., Spinar J., Zhang J., Zhang Y., Kimura K., Tamura K., Gayat E., Mebazaa A; GREAT (Global Research on Acute Conditions Team) Network. East Asia may have a better 1-year survival following an acute heart failure episode compared with Europe: results from an international observational cohort. European Journal of Heart Failure 2018;20(6):1071-1075.IF 6.968 Q1
  18. Harjola VP, Parissis J, Brunner-La Rocca HP, Čelutkienė J, Chioncel O, Collins SP, De Backer D, Filippatos GS, Gayat E, Hill L, Lainscak M, Lassus J, Masip J, Mebazaa A, Miró Ò, Mortara A, Mueller C, Mullens W, Nieminen MS, Rudiger A, Ruschitzka F, Seferovic PM, Sionis A, Vieillard-Baron A, Weinstein JM, de Boer RA, Crespo Leiro MG, Piepoli M, Riley JP. Comprehensive in-hospital monitoring in acute heart failure: applications for clinical practice and future directions for research. A statement from the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). European Journal of Heart Failure 2018;20(7):1081-1099. IF 10.683 Q1
  19. Shkolnik E., Burneikaitė G., Jakutis G., Scherbak M., Zuozienė G., Petrauskienė B., Trush E., Vasyuk Y., Laucevičius A., Čelutkienė J. A randomized, triple-blind trial of cardiac shock-wave therapy on exercise tolerance and symptoms in patients with stable angina pectoris. Coronary Artery Disease 2018;29(7):579-586. IF 1.335 Q4
  20. Lycholip E., Aamodt I.T., Lie I., Šimbelytė T., Puronaitė R., Hillege H., de Vries A., Kraai I., Stromberg A., Jaarsma T., Čelutkienė J. The dynamics of self-care in the course of heart failure management: data from the INTOUCHstudy. Patient Preference and Adherence 2018:12;1113–1122. IF 1.798 Q3
  21. Scali MC, Ciampi Q, Picano E, Bossone E, Ferrara F, Citro R, Colonna P, Costantino MF, Cortigiani L, Andrea A, Severino S, Dodi C, Gaibazzi N, Galderisi M, Barbieri A, Monte I, Mori F, Reisenhofer B, Re F, Rigo F, Trambaiolo P, Amor M, Lowenstein J, Merlo PM, Daros CB, de Castro E Silva Pretto JL, Miglioranza MH, Torres MAR, de Azevedo Bellagamba CC, Chaves DQ, Simova I, Varga A, Čelutkienė J, Kasprzak JD, Wierzbowska-Drabik K, Lipiec P, Weiner-Mik P, Szymczyk E, Wdowiak-Okrojek K, Djordjevic-Dikic A, Dekleva M, Stankovic I, Neskovic AN, Zagatina A, Di Salvo G, Perez JE, Camarozano AC, Corciu AI, Boshchenko A, Lattanzi F, Cotrim C, Fazendas P, Haberka M, Sobkowic B, Kosmala W, Witkowski T, Gosciniak P, Salustri A, Rodriguez-Zanella H, Leal LIM, Nikolic A, Gligorova S, Urluescu ML, Fiorino M, Novo G, Preradovic-Kovacevic T, Ostojic M, Beleslin B, Villari B, De Nes M, Paterni M, Carpeggiani C. Stress Echo 2020 study group of the Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI). Quality control of B-lines analysis in stress Echo 2020. Cardiovascular Ultrasound 2018;16(1):20. IF 2.051 (IMC) IF 1.652 Q3
  22. Čelutkienė J., Plymen C.M., Flachskampf F.A., de Boer R.A., Grapsa J., Manka R., Anderson L., Garbi M., Barberis V., Filardi P.P., Gargiulo P., Zamorano J.L., Lainscak M., Seferovic P., Ruschitzka F., Rosano G.M.C., Nihoyannopoulos P. Innovative imaging methods in heart failure: a shifting paradigm in cardiac assessment. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure 2018;20(12):1615-1633. IF 10.683 (IMC) Q1
  23. Aamodt I.T., Lycholip E., Čelutkienė J., Strömberg A., Atar D., Falk R.S., von Lueder T., Hellesø R., Jaarsma T., Lie I. Health Care Professionals’ Perceptions of Home Telemonitoring in Heart Failure Care: Cross-Sectional Survey. Journal of Medical Internet Research 2019;21(2):e10362. IF 4.671 Q1
  24. Seferović P.M., Polovina M., Bauersachs J., Arad M., Gal T.B., Lund L.H., Felix S.B., Arbustini E., Caforio A.L.P., Farmakis D., Filippatos G.S., Gialafos E., Kanjuh V., Krljanac G., Limongelli G., Linhart A., Lyon A.R., Maksimović R., Miličić D., Milinković I., Noutsias M., Oto A., Oto Ö., Pavlović S.U., Piepoli M.F., Ristić A.D., Rosano G.M.C., Seggewiss H., Ašanin M, Seferović J.P., Ruschitzka F., Čelutkienė J., Jaarsma T., Mueller C., Moura B., Hill L., Volterrani M., Lopatin Y., Metra M., Backs J., Mullens W., Chioncel O., de Boer R.A., Anker S., Rapezzi C., Coats A.J.S., Tschöpe C. Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure 2019;21(5):553-576. IF 10.683 Q1Simonavičius J., Sanders van-Wijk S., Rickenbacher P., Maeder M.T., Pfister O., Kaufmann B.A., Pfisterer M., Čelutkienė J., Puronaitė R., Knackstedt C., van Empel V., Rocca H.B. Prognostic significance of longitudinal clinical congestion pattern in chronic heart failure: insights from TIME-CHF trial. The American Journal of Medicine 2019; 132(9):E679-E692. IF 4.76 Q1
  25. Lycholip E., Palevičiūtė E., Aamodt I.T., Hellesø R., Lie I., Strömberg A., Jaarsma T., Čelutkienė J. Non-invasive home lung impedance monitoring in early post-acute heart failure discharge: Three case reports. World Journal of Clinical Cases 2019;7(8):951-960. IF 1.153 Q3
  26. Čelutkienė J., Burneikaitė G., Shkolnik E., Jakutis G., Vajauskas D., Čerlinskaitė K., Zuozienė G., Petrauskienė B., Puronaitė R., Komiagienė R., Butkuvienė I., Steponėnienė R., Misiūra J., Laucevičius A. The effect of cardiac shock wave therapy on myocardial function and perfusion in the randomized, triple-blind, sham-procedure controlled study. Cardiovascular Ultrasound 2019;17(1):13. IF 2.043 Q3
  27. Kimmoun A., Cotter G., Davison B., Takagi K., Addad F., Čelutkienė J., Chioncel O., Solal A.C., Diaz R., Damasceno A., Duengen H.D., Filippatos G., Goncalvesova E., Merai I., Metra M., Ponikowski P., Privalov D, Sliwa K., Sani M.U., Voors A.A., Shogenov Z., Mebazaa A. Safety, Tolerability and efficacy of Rapid Optimization, helped by NT-proBNP and GDF-15, of Heart Failure therapies (STRONG-HF): rationale and design for a multicentre, randomized, parallel-group study. European Journal of Heart Failure 2019;21(11):1459-1467. IF 12.129 Q1
  28. Čelutkienė J., Spoletini I., Coats A.J.S., Chioncel O. Left ventricular function monitoring in heart failure. European Heart Journal Supplements 2019;21(Suppl M):M17-M19. IF 1.655 Q3
  29. Čelutkienė J., Lainscak M., Anderson L., Gayat E., Grapsa J., Harjola V.P., Manka R., Nihoyannopoulos P., Filardi P.P., Vrettou R., Anker S.D., Filippatos G., Mebazaa A., Metra M., Piepoli M. Ruschitzka F., Zamorano J.L., Rosano G., Seferovic P. Imaging in patients with suspected acute heart failure: timeline approach position statement on behalf of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure 2020;22(2):181-195.  IF 11.627 Q1
  30. Aamodt I.T., Lycholip E., Čelutkienė J.,  von Lueder T.,  Atar D., Falk R.S.,  Hellesø R.,  Jaarsma T., Strömberg A., Lie I. Self-Care Monitoring of Heart Failure Symptoms and Lung Impedance at Home Following Hospital Discharge: Longitudinal Study. Journal of Medical Internet Research 2020;22(1):e15445.[14 p.] IF 4.945 Q1
  31. Motiejūnaitė J, Akiyama E, Cohen-Solal A, Maggioni AP, Mueller C, Choi DJ, Kavoliūnienė A, Čelutkienė J, Parenica J, Lassus J, Kajimoto K, Sato N, Miró Ò, Peacock WF, Matsue Y, Voors AA, Lam CSP, Ezekowitz JA, Ahmed A, Fonarow GC, Gayat E, Regitz-Zagrosek V, Mebazaa A. The association of long-term outcome and biological sex in patients with acute heart failure from different geographic regions. European Heart Journal 2020;41(13):1357-1364. IF 24.889 Q1
  32. Takagi K., Miró Ò., Gayat E., Llorens P., Wussler D.N., Čerlinskaitė K., Msolli M.A., Kavoliūnienė A., Sekma A., Čelutkienė J., Nouira S., Gil V., Martínez-Nadal G., Breidthardt T., Kozhuharov N., Martin J., Müller C., Mebazaa A. Safety of Diuretic Administration during the Early Management of Dyspnea Patients Who Are Not Finally Diagnosed with Acute Heart Failure. European Journal of Emergency Medicine 2020;27(6):422-428. IF 1.383 Q3
  33. Harjola VP, Parissis J, Bauersachs J, Brunner-La Rocca HP, Bueno H, Čelutkienė J, Chioncel O, Coats AJS, Collins SP, de Boer RA, Filippatos G, Gayat E, Hill L, Laine M, Lassus J, Lommi J, Masip J, Mebazaa A, Metra M, Miró Ò, Mortara A, Mueller C, Mullens W, Peacock WF, Pentikäinen M, Piepoli MF, Polyzogopoulou E, Rudiger A, Ruschitzka F, Seferovic P, Sionis A, Teerlink JR, Thum T, Varpula M, Weinstein JM, Yilmaz MB. Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure  2020 Apr 29. doi: 10.1002/ejhf.183 IF 11.627 Q1
  34. Chioncel O, Parissis J, Mebazaa A, Thiele H, Desch S, Bauersachs J, Harjola VP, Antohi EL, Arrigo M, Gal TB, Čelutkienė J., Collins SP, DeBacker D, Iliescu VA, Jankowska E, Jaarsma T, Keramida K, Lainscak M, Lund LH, Lyon AR, Masip J, Metra M, Miro O, Mortara A, Mueller C, Mullens W, Nikolaou M, Piepoli M, Price S, Rosano G, Vieillard-Baron A, Weinstein JM, Anker SD, Filippatos G, Ruschitzka F, Coats AJS, Seferovic P. Epidemiology, pathophysiology and contemporary management of cardiogenic shock – a position statement from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure  2020 May 29. doi: 10.1002/ejhf.1922. IF 11.627 Q1
  35. Kažukauskienė I, Baltrūnienė V, Jakubauskas A, Žurauskas E, Maneikienė VV, Daunoravičius D, Čelutkienė J, Ručinskas K, Grabauskienė V. Prevalence and prognostic relevance of myocardial inflammation and cardiotropic viruses in non-ischemic dilated cardiomyopathy. Cardiology Journal 2020 Jun 22. doi: 10.5603/CJ.a2020.0088. IF 1.669 Q3
  36. Seferović PM, Fragasso G, Petrie M, Mullens W, Ferrari R, Thum T, Bauersachs J, Anker SD, Ray R, Çavuşoğlu Y, Polovina M, Metra M, Ambrosio G, Prasad K, Seferović J, Jhund PS, Dattilo G, Čelutkiene J, Piepoli M, Moura B, Chioncel O, Gal TB, Heymans S, De Boer RA, Jaarsma T, Hill L, Lopatin Y, Lyon AR, Ponikowski P, Lainščak M, Jankowska E, Mueller C, Cosentino F, Lund L, Filippatos GS, Ruschitzka F, Coats AJS, Rosano GMC. Sodium glucose co-transporter-2 inhibitors in heart failure: beyond glycaemic control. The Position Paper of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure  2020 Jul 2. doi: 10.1002/ejhf.1954 IF 11.627 Q1
  37. Baušys A., Lukšta M., Kuliavas J., Anglickienė G., Maneikienė V., Gedvilaitė L., Čelutkienė J., Jamontaitė I., Cirtautas A., Lenickienė S., Vaitkevičiūtė D., Gavelienė E., Klimavičiūtė G., Baušys R., Strupas K. Personalized trimodal prehabilitation for gastrectomy. Medicine (Baltimore) 2020;99(27):e20687. IF 1.552 Q3
  38. Čelutkienė J., Pudil R, López-Fernández T, Grapsa J, Nihoyannopoulos P, Bergler-Klein J, Cohen-Solal A, Farmakis D, Tocchetti CG, von Haehling S, Barberis V, Flachskampf FA, Čeponienė I, Haegler-Laube E, Suter T, Lapinskas T, Prasad S, de Boer RA, Wechalekar K, Anker MS, Iakobishvili Z, Buccarelli-Ducci C, Schulz-Menger J, Cosyns B, Gaemperli O, Belenkov Y, Hulot JS, Galderisi M, Lancellotti P, Bax J, Marwick TH, Chioncel O, Jaarsma T, Mullens W, Piepoli M, Thum T, Heymans S, Mueller C, Moura B, Ruschitzka F, Zamorano JL, Rosano G, Coats AJS, Asteggiano R, Seferovic P, Edvardsen T, Lyon AR. The role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a Position statement on behalf of the Heart Failure Association (HFA), the European Association of Cardiovascular Imaging (EACVI) and the Cardio-Oncology Council of the European Society of Cardiology (ESC). European Journal of Heart Failure 2020;22(9):1504-1524. IF 11.627 Q1
  39. Bombardini T, Zagatina A, Ciampi Q, Cortigiani L, D’andrea A, Borguezan Daros C, Zhuravskaya N, Kasprzak JD, Wierzbowska-Drabik K, De Castro E Silva Pretto JL, Djordjevic-Dikic A, Beleslin B, Petrovic M, Boskovic N, Tesic M, Monte IP, Simova I, Vladova M, Boshchenko A, Ryabova T, Citro R, Amor M, Vargas Mieles PE, Arbucci R, Dodi C, Rigo F, Gligorova S, Dekleva M, Severino S, Torres MA, Salustri A, Rodrìguez-Zanella H, Costantino FM, Varga A, Agoston G, Bossone E, Ferrara F, Gaibazzi N, Rabia G, Čelutkienė J., Haberka M, Mori F, D’alfonso MG, Reisenhofer B, Camarozano AC, Salamé M, Szymczyk E, Wejner-Mik P, Wdowiak-Okrojek K, Kovacevic Preradovic T, Lattanzi F, Morrone D, Scali MC, Ostojic M, Nikolic A, Re F, Barbieri A, Di Salvo G, Colonna P, De Nes M, Paterni M, Merlo PM, Lowenstein J, Carpeggiani C, Gregori D, Picano E; Stress Echo 2020 study group of the Italian Society of Echocardiography and Cardiovascular Imaging. Feasibility and value of two-dimensional volumetric stress echocardiography. Minerva Cardioangiologica 2020 Jul 10. doi: 10.23736/S0026-4725.20.05304-9. Online ahead of print.PMID: 32657562 IF 0.713 Q4
  40. Scali MC, Zagatina A, Ciampi Q, Cortigiani L, D’Andrea A, Daros CB, Zhuravskaya N, Kasprzak JD, Wierzbowska-Drabik K, Luis de Castro E Silva Pretto J, Djordjevic-Dikic A, Beleslin B, Petrovic M, Boskovic N, Tesic M, Monte I, Simova I, Vladova M, Boshchenko A, Vrublevsky A, Citro R, Amor M, Vargas Mieles PE, Arbucci R, Merlo PM, Lowenstein Haber DM, Dodi C, Rigo F, Gligorova S, Dekleva M, Severino S, Lattanzi F, Morrone D, Galderisi M, Torres MAR, Salustri A, Rodrìguez-Zanella H, Costantino FM, Varga A, Agoston G, Bossone E, Ferrara F, Gaibazzi N, Čelutkienė J., Haberka M, Mori F, D’Alfonso MG, Reisenhofer B, Camarozano AC, Miglioranza MH, Szymczyk E, Wejner-Mik P, Wdowiak-Okrojek K, Preradovic-Kovacevic T, Bombardini T, Ostojic M, Nikolic A, Re F, Barbieri A, Di Salvo G, Merli E, Colonna P, Lorenzoni V, De Nes M, Paterni M, Carpeggiani C, Lowenstein J, Picano E; Stress Echo 2020 Study Group of the Italian Society of Echocardiography and Cardiovascular Imaging. Lung Ultrasound and Pulmonary Congestion During Stress Echocardiography. JACC Cardiovascular Imaging 2020 Jul 15:S1936-878X(20)30410-1. IF 12.74 Q1
  41. Heliö T, Elliott P, Koskenvuo JW, Gimeno JR, Tavazzi L, Tendera M, Kaski JP, Mansencal N, Bilińska Z, Carr-White G, Damy T, Frustaci A, Kindermann I, Ripoll-Vera T, Čelutkienė J., Axelsson A, Lorenzini M, Saad A, Maggioni AP, Laroche C, Caforio ALP, Charron P; EORP Cardiomyopathy Registry Investigators Group. ESC EORP Cardiomyopathy Registry: real-life practice of genetic counselling and testing in adult cardiomyopathy patients. ESC Heart Failure 2020;7(5):3013-3021. IF 3.902 Q2
  42. Hill L, Prager Geller T, Baruah R, Beattie JM, Boyne J, de Stoutz N, Di Stolfo G, Lambrinou E, Skibelund AK, Uchmanowicz I, Rutten FH, Čelutkienė J, Piepoli MF, Jankowska EA, Chioncel O, Ben Gal T, Seferovic PM, Ruschitzka F, Coats AJS, Strömberg A, Jaarsma T. Integration of a palliative approach into heart failure care: a European Society of Cardiology Heart Failure Association position paper. European Journal of Heart Failure 2020 Sep 6. doi: 10.1002/ejhf.1994. [p.1-13]. IF 11.627 Q1
  43. Jaarsma T, Hill L, Bayes-Genis A, Brunner La Rocca HP, Castiello T, Čelutkienė J, Marques-Sule E, Plymen CM, Piper SE, Riegel B, Rutten FH, Ben Gal T, Bauersachs J, Coats A, Chioncel O, Lopatin Y, Lund LH, Lainscak M, Moura B, Mullens W, Piepoli MF, Rosano G, Seferovic P, Strömberg A. Self-care of heart failure patients: practical management recommendations from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure 2020 Sep 18. doi: 10.1002/ejhf.2008. [p.1-41]. IF 11.627 Q1
  44. Jaarsma T, Čelutkienė J, Lopatin Y, Vugrak L, Hill L, Strömberg A, Coats AJ. Learning together: insights from the first Heart Failure Association Patient Forum. European Journal of Heart Failure 2020 Sep 23. doi: 10.1002/ejhf.2013. [p.1-5]. IF 11.627 Q
  45. Pudil R, Mueller C, Čelutkienė J., Henriksen PA, Lenihan D, Dent S, Barac A, Stanway S, Moslehi J, Suter TM, Ky B, Štěrba M, Cardinale D, Cohen-Solal A, Tocchetti CG, Farmakis D, Bergler-Klein J, Anker MS, Von Haehling S, Belenkov Y, Iakobishvili Z, Maack C, Ciardiello F, Ruschitzka F, Coats AJS, Seferovic P, Lainscak M, Piepoli MF, Chioncel O, Bax J, Hulot JS, Skouri H, Hägler-Laube ES, Asteggiano R, Fernandez TL, de Boer RA, Lyon AR. The role of serum biomarkers in cancer patients receiving cardiotoxic cancer therapies: a position statement from the Cardio-Oncology Study Group of the Heart Failure Association and Cardio-Oncology Council of the European Society of Cardiology. European Journal of Heart Failure 2020 Oct 2. doi: 10.1002/ejhf.2017. IF 11.627 1Q
  46. de Boer RA, Hulot JS, Tocchetti CG, Aboumsallem JP, Ameri P, Anker SD, Bauersachs J, Bertero E, Coats AJS, Čelutkienė J, Chioncel O, Dodion P, Eschenhagen T, Farmakis D, Bayes-Genis A, Jäger D, Jankowska EA, Kitsis RN, Konety SH, Larkin J, Lehmann L, Lenihan DJ, Maack C, Moslehi JJ, Müller OJ, Nowak-Sliwinska P, Piepoli MF, Ponikowski P, Pudil R, Rainer PP, Ruschitzka F, Sawyer D, Seferovic PM, Suter T, Thum T, van der Meer P, Van Laake LW, von Haehling S, Heymans S, Lyon AR, Backs J. Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur J Heart Fail. 2020 Oct 22. doi: 10.1002/ejhf.2029. Online ahead of print.
  47. Simonavičius J, Maeder MT, Eurlings CGMJ, Aizpurua AB, Čelutkienė J, Barysienė J, Toggweiler S, Kaufmann BA, Brunner-La Rocca HP. Intensification of pharmacological decongestion but not the actual daily loop diuretic dose predicts worse chronic heart failure outcome: insights from TIME-CHF. Clinical Research In Cardiology 2020 Nov 20. doi: 10.1007/s00392-020-01779-7 IF 5.268 Q1
Projects
  1. “Naujųjų arterinių žymenų prognostinės vertės, numatant kairiojo skilvelio diastolinės disfunkcijos atsiradimą ir progresavimą bei kardiovaskulinius įvykius, tyrimas”
  2. “Miokardo smūginės bangos terapijos efektyvumas gydant pacientus su stabilia krūtinės angina”
  3. “ISCHEMIA”: standartinio medikamentinio ir invazinio stabilios krūtinės anginos gydymo palyginimas.
  4. ,,Hospitalizuojamų dėl ūminio širdies nepakankamumo pacientų kohortinis daugiacentris prospektyvinis stebėsenos ir serologinių biožymenų tyrimas“
  5. „Inovacijos, orientuotos į vartotoją – pacientų, sergančių širdies nepakankamumu, simptomų monitoravimas po hospitalizacijos – NordicBaltic tyrimas“
  6. ,,COVID-19 pandemijos įtaka žmogaus ir visuomenės sveikatai bei sveikatos apsaugos sistemos funkcionavimui: kraujotakos sistemos ligų atvejo analizė“.

PhD Rita Rugienė

Senior researcher

Deputy Director for Scientific Affairs, Junior Researcher (project)
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Anžela Slušnienė

Deputy Director for Scientific Affairs, Junior Researcher (project)

Education

 Kaunas Medical Academy, postgraduate in internal medicine specialty – doctor internist;
Mykolas Romeris University – master’s degree of public administration;
2015–2021 PhD student at State Research Institute, Centre for Innovative Medicine.
The topic and institution of the defended work Pecularities diurnal of heart rate variability and blood pressure fluctuations in subjects with arterial hypertension and concomitant metabolic syndrome, State Resaech Institute Centre for Innovative Medicine.
Employment State Research Institute, Centre for Innovative Medicine – PhD student and different research projects. Privat clinic Inmedica doctor internist.
Publications
  1. Lugin S., Slušnienė A., …// Proceedings of International Conference. Biomedical Engineering-2001. Kaunas University of Technology. Technologija. 2001, pp. 4;
  2. Lugin S., Slušnienė A., …// Proceedings of International Conference. Biomedical Engineering-2002. Kaunas University of Technology. Technologija. 2002, pp. 4;
  3. Lugin S., Slušnienė A., …// Proceedings of International Conference. Biomedical Engineering-2003. Kaunas University of Technology. Technologija. 2003, pp. 4;
  4. Lugin S., Slušnienė A., Girčys R., Vrubliauskas A. A mechanical – mathematical model of the “Heart-blood flow-Aorta” system with one-degree-of freedom of constrained oscillation. // Proceedings of International Conference. Biomedical Engineering-2004. Kaunas University of Technology. Technologija. 2004, pp. 41-45;
  5. Lugin S., Slušnienė A., Girčys R., Vrubliauskas A. Hooke‘s law application in vascular evalution. // Proceedings of International Conference. Biomedical Engineering-2005. Kaunas University of Technology. Technologija. 2005, pp. 169-172;
  6. Girčys R., Lugin S., VrubliauskasA..Slušnienė A. Algebraic model of arterial pressure pulse wave in “Heart-Aorta-Artery” system. // Proceedings of International Conference. Biomedical Engineering-2006. Kaunas University of Technology. Technologija. 2006, pp. 269-272;
  7. Lugin S., Stankus A., Girčys R., Slušnienė A. Arterial pulse wave as function of stroke volume. // Proceedings of International Conference. Biomedical Engineering-2007. Kaunas University of Technology. Technologija. 2007, pp. 24-26;
  8. Lugin S., Stankus A., Girčys R., Slušnienė A. Systolic arterial blood mass and velocity relationship. // Proceedings of International Conference. Biomedical Engineering – 2008. Kaunas University of Technology. Technologija. 2008, pp. 94-96;
  9. Albinas Stankus, Anžela Slušnienė Cortisol and Stress Consequences. Review // Biological Psychiatry and Psychopharmacology. – vol. 11, Nr. 1, 2009;11:9-20;
  10. Šerpytis Pranas; Tamošiūnas Tomas; Slušnienė Anžela; Glaveckaitė Sigita; Kezytė Greta; Urbanavičiūtė Indrė; Laucevičius Aleksandras Public knowledge concerning cardiopulmonary resuscitation and automated external defibrillator skills in Lithuania. Visuomenės žinios apie pradinį gaivinimą ir automatinių išorinių defibriliatorių naudojimą Lietuvoje // Sveikatos mokslai. Vilnius : Sveikatos mokslai. 2016, T. 26, nr. 4, p. 35-40;
  11. Šerpytis Pranas; Tamošiūnas Tomas; Slušnienė A.; Kezytė Greta; Urbanavičiūtė Indrė; Šerpytis Rokas; Laucevičius Aleksandras Public knowledge concerning cardiopulmonary resuscitation and automated external defibrillator skills in Lithuania // Global heart. Amsterdam: 2016, Vol. 11, Iss. 2, suppl, p. e180;
  12. Laucevičius, A. Slušnienė State Resaech Institute Centre for Innovative Medicine; Lithuania, Assessment of relationship between the daily physical activity, heart rate and blood pressure in patients with hypertension, 12th International Conference Program & Abstract Book May 4-6 th, 2017 Klaipeda, Lithuania;
  13. Laucevičius, A. Slušnienė State Resaech Institute Centre for Innovative Medicine ,,Assessment of the relationship between the blood pressure and heart rate variability in patients with hypertension”, 26th Nordic-Baltic Congress of Cardiology 2017 1-3 June 2017, | Vilnius, Lithuania;
  14. Slušnienė, A.; Laucevičius, A.; Navickas, P.; Ryliškytė, L.; Stankus, V.; Stankus, A.; Navickas, R.; Laucevičienė, I.; Kasiulevičius, V. Daily Heart Rate Variability Indices in Subjects with and Without Metabolic Syndrome Before and After the Elimination of the Influence of Day-time Physical Activity. Medicina, 2019, 55, 700;
  15. Anžela Slušnienė, Petras Navickas State Resaech Institute Centre for Innovative Medicine, Vilnius University, Faculty of Medicine Accurately pinpointing the nocturnal period in 24-hour ambulatory blood pressure monitoring by using of actigraphy, 7th International virtual Conference on Prehypertension, Hypertension, Metabolic Disorders and Cardiovascular Disease, which will take on November 20-22, 2020;
  16. Slušnienė Anžela; Navickas Petras; Stankus Albinas; Laucevičienė Ieva; Ryliškytė Ligita; Laucevičius Aleksandras Defining the nocturnal period in 24-h ambulatory blood pressure monitoring: a comparison of three methods // Blood pressure monitoring. Philadelphia: Lippincot Williams & Wilkins. 2021, first published online, p. [1-5].
Projects Research projects:
Determination of anaerobic threshold by studying the dynamics of heart rate variability to assess physical capacity;
Development of a self-monitoring and remote monitoring system for hypertensive patients.
Areas of interest, directions of cooperation

Circadian rhythm; physical activity; heart rate variability; ambulatory 24-hour blood pressure ir ECG monitoring, arterial hypertension; different health monitoring system and ect.

Rheumatologist
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Regina Šakalytė

Rheumatologist

Education

 Degree of Master
Employment Vilnius University Hospital Santaros Klinikos; Centre for Innovative Medicine
Areas of interest, directions of cooperation

Early unidifferentiated arthritis

Chief Researcher
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Prof. Jolanta Dadonienė

Chief Researcher

Education

 Professor, senior researcher
The topic and institution of the defended work Habiltation procedure: Vasculitis epidemiology, diagnostics and clinic, Vilnius university, 2006
Employment Data analysis in rheumatic disease, research methodology
Publications 7 Claryvate Analytics database publications during last five years
Areas of interest, directions of cooperation

Rheumatic diseases, epidemiology of chronic diseases

Researcher
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PhD Alma Čypienė

Researcher
Education Higher education + Ph.Dr. studies
The topic and institution of the defended work Institute of Experimental and Clinical medicine at Vilnius University 2008 m. „Endothelial function and arterial stiffness disorders in systemic rheumatic diseases“
Employment Researcher
Publications ISI publication 9, Index Copernicus 36, other – 62
Projects „ĮVAIRAUS DIAMETRO ARTERIJŲ FUNKCIJOS BEI STRUKTŪROS PAŽEIDIMO ASPEKTAI SERGANT SISTEMINE SKLEROZE“
„REUMATINĖS LIGOS IR ŠIRDIES-KRAUJAGYSLIŲ FUNKCINIAI IR STRUKTŪRINIAI POKYČIAI“.
“VITAMINO D, METABOLINIO SINDROMO IR KAULŲ TANKIO RYŠYS SU ANKSTYVA ATEROSKLEROZE”
“LAZERINĖS ŠVIESOS SINDULIUOTĖS GYDOMOJO POVEIKIO PAIEŠKA: SISTEMINE SKLEROZE SERGANČIŲJŲ ODOS ELASTINGUMUI, MIKROCIRKULIACIJAI GERINTI”
„Pacientų po miokardo infarkto gyvenimo ir gydymo kokybės įvertinimas“.
„Hiperurikemijos ryšys su arterijų funkciniais ir struktūriniais rodikliais pacientams, kuriems nustatytas metabolinis sindromas“
„ŠIRDIES-KRAUJAGYSLIŲ FUNKCINIŲ IR STRUKTŪRINIŲ POKYČIŲ PROGRESAVIMAS, SERGANT SISTENINE SKLEROZE“
Areas of interest, directions of cooperation Cardiology, angiology. Non invasive investigation of peripherial arteries (endothelial function, arterial stiffness) in rheumatic patients. Comunication with Vilnius University, medical faculty, Santaros Clinics.

Junior Researcher
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PhD Dalia Miltinienė

Junior Researcher
Education

Vilnius University,Faculty of Medicine 1993-1999
The topic and institution of the defended work The prevalence of inflammatory rheumatic diseases in Vilnius, Lithuania. 2009. Vilnius University institute of experimental and clinical medicine
Employment 1. Vilnius University Hospital Santaros Clinics – Rheumatologist
2. Vilnius University
Faculty of Medicine – Assistant professor,
Research fellow
3. State Research Institute Centre for Innovative Medicine – Junior research fellow
Projects Associatons between rheumatic diseases, tuberculosis and cancer
Areas of interest, directions of cooperation

Epidemiology of rheumatic diseases

Biostatistician (project)
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Roma Puronaitė

Biostatistician (project)
Education Master‘s degree (Statistics)
PhD student (Informatics)
The topic and institution of the defended work Master Thesis: T Wave Alternans Analysis Using a Modified Moving Average Method: a Comparison of Various Time Series Alignment and Similarity Detection Techniques
Employment Biostatistician
Publications http://www.elaba.mb.vu.lt/mf/?aut=Roma+Puronait%C4%97
https://scholar.google.com/citations?user=9_ehwZ0AAAAJ&hl=lt
Projects Development of a Personalized Physical Activity Efficiency Assessment Tool and Development of Application Methodology (2017-2019)
Determination of the Anaerobic Threshold by Studying the Dynamics of Heart Rate Variability to Assess the Physical Capacity (2020 – 2022)
Areas of interest, directions of cooperation

Research interests: machine learning, data mining, time series analysis.

ResearchGate: https://www.researchgate.net/profile/Roma-Puronaite

 

PhD Diana Mieliauskaitė Head of department, chief researcher, otorhinolaryngologist
Prof. Aleksandras Laucevičius Chief Researcher
Prof. PhD Jelena Čelutkienė Chief Researcher
Prof. PhD Jolanta Dadonienė Chief Researcher
PhD Gailutė Kirdaitė Senior Researcher
PhD Rita Rugienė Senior Researcher
PhD Alma Čypienė Researcher
PhD Sigita Stropuvienė Researcher
PhD Ramūnas Janavičius Researcher
Anžela Slušnienė Deputy Director for Scientific Affairs, Junior Researcher (project)
PhD Dalia Miltinienė Junior Researcher
Petras Navickas Junior Researcher (project)
Regina Šakalytė Rheumatologist
Skirmantė Rusonienė Junior Researcher,Pediatric Rheumatologist
Roma Puronaitė Biostatistician (project)
Kristina Galiauskienė Laboratory  Assistant
Lijana Gerasimienė General Practice Nurse
Irena Voronecka General Practice Nurse
Beatričė Valatkaitė – Rakštienė PhD Candidate
Ieva Talijūnienė doktorantas
Jurgita Mikolaitytė PhD Candidate
Simonita Alaburdė PhD Candidate
Vija Vainutienė PhD Candidate